沐舒坦联合舒利迭对慢性阻塞性肺疾病急性加重期患者肺功能和血气分析的影响  

Influence of mucosolvan and seretide on pulmonary function and blood gas analysis of patients with acute exacerbations of chronic obstructive pulmonary disease

作　　者：罗进[1] 

机构地区：[1]内江市第一人民医院呼吸科,四川省641000

出　　处：《中华临床医师杂志（电子版）》2014年第5期52-55,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨沐舒坦联合舒利迭对慢性阻塞性肺疾病急性加重期(AECOPD)患者肺功能和血气分析的影响。方法 138例AECOPD患者随机分为3组,对照组1给予基础常规治疗加沐舒坦雾化,对照组2予基础常规治疗加吸入舒利迭,试验组除了基础常规治疗外通过吸入舒利迭并联合沐舒坦雾化,比较三组患者肺功能及血气分析变化。结果所有患者肺功能及血气分析指标均较治疗前有所改善(P<0.05)。治疗后72 h、治疗后2周,对照组1与对照组2比较肺功能及血气分析指标均无明显差异(P>0.05),而试验组与对照组1、对照组2比较,差异有显著性意义(P<0.05)。结论在常规治疗基础上,联用沐舒坦和舒利迭可较单用其中一种药物更利于改善AECOPD患者肺功能及血气分析指标,值得临床广泛应用。Objective To discuss the influence of mucosolvan and seretide on pulmonary function and blood gas analysis of patients with acute exacerbations of chronic obstructive pulmonary disease. Methods 138 patients of acute exacerbations of chronic obstructive pulmonary disease were randomly divided into three groups. Besides the routine treatment, the patients of the control group 1 inhaled mucosolvan alone, the patients of the control group 2 inhaled seretide alone, and the patients of the experimental group inhaled both mucosolvan and seretide. After therapy, indexes of pulmonary function and blood gas analysis were compared respectively. Results After treatment, the indexes of pulmonary function and blood gas analysis of all patients improved better than before. The indexes of the experimental group were much better than that of the control group 1 and the control group 2, while there was no statistical difference in the latter two groups. Conclusions Base on the routine treatment, combination therapy with mucosolvan and seretide can improve the indexes of pulmonary function and blood gas analysis of AECOPD patients better than with mucosolvan or seretide alone, which is worthy to be widely used in clinical treatment.

关 键 词：肺疾病 慢性阻塞性 血气分析 沐舒坦 舒利迭 肺功能 

分 类 号：R563.9[医药卫生—呼吸系统]