骨折手术预防性应用抗菌药物药物经济学分析  

Pharmacoeconomic Analysis of Common Antibiotics for Preventing Post-operation Infection

作　　者：苏雪芳 张玉娥[1,2] 

机构地区：[1]广东省江门市五邑中医院药剂科 [2]暨南大学医学院第六附属医院,江门529000

出　　处：《北方药学》2014年第5期87-88,共2页Journal of North Pharmacy

摘　　要：目的:探讨应用3种常用抗菌药物预防手术感染的经济效果,促进抗菌药物合理使用,降低医疗费用。方法:采用回顾性调查方法,随机抽取2012年及2013年骨折手术预防感染病例255份进行分析,运用药物经济学原理对3种最常用的抗菌药物头孢硫脒、头孢孟多酯钠、头孢替唑钠预防手术感染的成本-效果进行比较分析。结果:在最常用的3种抗菌药物中,头孢硫脒为最佳用药选择。结论:头孢硫脒在本次分析中具有成本效果优势,可作为选择治疗方案的参考。Objective： To investigate the economic effectiveness of three commonly-used antibiotics to prevent operation infections, promote reasonable and standard usage of antibiotics surround operation and decrease medical cost. Methods： In reviewing and investigating 255 cases at random for preventing infection in orthopaedics operation in 2012 and 2013. We analysed comparatively the most commonly-used three kinds of antibiotics Cefathiamidine,Ceftezole Sodium,Cefamandole Nafate among these 255 cases by cost-effectiveness in Pharmacoeconomics. Results： Among those three kinds of antimicrobial agents,Cefathiamidine is the optimal option.Conclusion：Cefathiamidine has an advantage in cost-effectiveness and can be used as reference.

关 键 词：抗菌药物 预防感染 药物经济学 成本-效果分析 

分 类 号：R96[医药卫生—药理学]