中国人群血清胰岛素参考区间的建立  

Establishment of Serum Insulin Reference Intervals for Chinese Adults

作　　者：付煜[1] 包丽华[1] 陈恒[2] 杨涛[2] 

机构地区：[1]南京医科大学第一附属医院核医学科,江苏南京210029 [2]南京医科大学第一附属医院内分泌科,江苏南京210029

出　　处：《标记免疫分析与临床》2014年第2期193-196,共4页Labeled Immunoassays and Clinical Medicine

基　　金：国家自然科学基金资助项目(81270897)

摘　　要：目的 建立符合中国人群的血清胰岛素参考区间.方法 对10027名南京市鼓楼区流行病学调查个体进行问卷调查、身体指标测量及血清学检测.最后,以纳入的1433名表观健康人群为参考人群,建立符合中国人群的血清胰岛素参考区间.结果 血清胰岛素水平与年龄无明显相关性,男性餐后30min和120min血清胰岛素水平均低于女性,空腹血清胰岛素水平在男性和女性间没发现明显差异.男性空腹、餐后30min、120min血清胰岛素参考区间分别为3.3～22.0 μIU/mL、13.6～164.9μ IU/mL、7.6 ～ 140.4μIU/mL,女性分别为3.4 ～ 28.2 μIU/mL、16.6 ～ 183.0μIU/mL、10.0～120.0μIU/mL,总体分别为3.3 ～ 26.1μIU/mL、16.2 ～ 179.5 μIU/mL、9.1～122.7μIU/mL.结论 人血清胰岛素水平与性别有关,建立符合中国人群的按性别区分的血清胰岛素参考区间对临床检测和诊断有重要的意义.Objective To establish the serum insulin reference intervals in Chinese adults.Methods 10027individuals were recruited and undertook questionnaires,physical examinations and Laboratory measurements in an epidemiological study.Finally,the insulin reference intervals were established with 1433 apparently healthy subjects who were justified as reference individuals.Results The difference of insulin levels were existed between male and female,while no correlation of insulin levels was observed with age in the healthy.Conclusion The insulin levels can be influenced by gender,and the gender-related insulin reference intervals for Chinese adults could provide valuable information for physicians in the diagnosis and treatment of diabetes.

关 键 词：胰岛素 参考区间 放射免疫分析 

分 类 号：R587.1[医药卫生—内分泌]