射频消融治疗合并重度肝硬化的小肝癌疗效分析  

Therapeutic effect of the radiofrequency ablation for treatment of hepatocellular carcinoma with severe cirrhosis

作　　者：钱瑞坤 乔森[3] 刘建刚[4] 

机构地区：[1]山东省医学科学院,山东济南250062 [2]济南大学山东省医学科学院医学与生命科学学院,济南250062 [3]济宁医学院附属济宁市第一人民医院,山东济宁272011 [4]济宁医学院临床学院,济宁272067

出　　处：《济宁医学院学报》2014年第2期97-99,共3页Journal of Jining Medical University

摘　　要：目的评估射频消融术治疗合并重度肝硬化的小肝癌临床应用价值。方法连续收集合并重度肝硬化的小肝癌患者64例,根据治疗方式不同分为射频消融组和手术切除组。回顾性分析比较两组患者的临床疗效及术后并发症、复发转移率。结果两组之间年龄、性别、术前肝功能分级、1a后肿瘤复发转移率和生存率比较,无显著性差异(P>0.05)。射频消融组手术时间、术中出血量、术后镇痛剂使用例数,住院时间均明显低于肝癌切除组(P<0.05)。肝癌切除组术后出血、顽固性腹水、肝功能衰竭等并发症发生率明显高于射频消融组(P<0.05)。结论合并重度肝硬化的小肝癌患者射频消融术的疗效与手术切除相当,且并发症少。Objective 64 small liver cancer patients with severe cirrhosis were divided into two groups：the ra- diofrequency ablation group and cancer resection group. Retrospective analysis and comparison were carried out be- tween the two groups of patients with clinical efficacy, postoperative complications and recurrence metastasis rate. Results Age, gender,liver function classification before operation, tumor recurrence and metastasis rate and sur- vival rate after 1 years wt, re similar in the two groups（P〉0.05）. In the radiofrequency ablation group,operation time,intraoperative bleeding, cases of using postoperative analgesic, hospital stay were significantly lower than those of the cancer resection group（P〈0.05）. Complications such as postoperative bleeding, refractory ascites, liv- er failure rate in cancer resection group were significantly higher than those of the radiofrequency ablation group （P〈0.05）. Conclusion The curative effect of radiofrequency ablation in treating small liver cancer patients with severe cirrhosis is similar to surgical resection,and has fewer complications.

关 键 词：射频消融术 小肝癌 肝硬化 

分 类 号：R657.3[医药卫生—外科学]