成都地区临床患者输血前传染性标志物检测结果10年同期对比分析  

Contrastive analysis on detection results of transfusion-transmitted infectious diseases between during past 10 years in Chengdu

作　　者：安静娜 李冬冬[1] 陈其霞[1] 王婷婷[1] 杨廷富[1] 朱思远[1] 陶传敏[1] 

机构地区：[1]四川大学华西医院实验医学科微生物实验室,四川成都610041

出　　处：《中国输血杂志》2014年第4期405-407,共3页Chinese Journal of Blood Transfusion

基　　金：国家自然科学基金青年项目(81301400/H1901)

摘　　要：目的了解临床患者输血前传染性标志物的检测结果及10年前后的变化情况。方法对154 545名患者进行输血前乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒抗体(抗-HCV)、人类免疫缺陷病毒抗体(抗-HIV)和梅毒螺旋体抗体(抗-TP)的检测,并与10年前同期数据进行对比分析。结果 HBsAg阳性16 031例(10.37%),抗-HCV阳性1 651例(1.07%),抗-HIV阳性589例(0.38%),抗-TP阳性3 198例(2.07%);与10年前数据对比,HBsAg阳性率降低,抗-HIV和抗-TP阳性率升高,抗-HCV阳性率无明显变化。结论 10年来我国血液传播性疾病的形势发生明显改变,常规检测受血者的血液传染性标志物对于预防和减少输血纠纷的发生有重要的意义。Objective To investigate the status of contagious serum markers in patients before blood transfusion, and to explore the change in infection ratesoverthe past ten years. Methods The contagious serum markers including HBsAg, anti- HCV,anti-HIV,and anti-TP were tested in 154 545 patients before blood transfusion with a comparison of the data collected a decade ago. Results The positive rates of HBsAg,anti-HCV,anti-HIV and anti-TP are 10.37%, 1.07% ,0.38% ,and 2. 07% ,respectively. There is a decrease in the positive rate of HBsAg,an increaseing trends in the positive rates of anti-HIV and anti-TP, and no significant changes found in the positive rate of anti-HCV, when retrospectively compared with data recorded 10 years ago. Conclusion The situation of transfusion-transmitted diseases has changed sharply in the past 10 years and the detection of the contagious serum markers in patients before blood transfusion has a great importance in the prevention and reduction of the transfusion-transmitted infectious diseases.

关 键 词：输血 HBsAg 抗-HCV 抗-HIV 抗-TP 标志物检测 

分 类 号：R446[医药卫生—诊断学]