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机构地区:[1]连云港市第一人民医院,江苏连云港222002
出 处:《中国药房》2014年第20期1877-1878,共2页China Pharmacy
摘 要:目的:观察常规药物联合体育疗法治疗慢性支气管炎的临床疗效和安全性。方法:102例慢性支气管炎患者按随机数字表法均分为对照组和试验组。对照组患者给予常规药物治疗:抗菌药物给予阿莫西林0.5g,bid或罗红霉素0.3g,bid;镇咳祛痰给予复方甘草合剂10ml,tid,视病情改善情况加用溴乙新8~16mg,tid;平喘给予氨茶碱0.1g,tid。试验组患者在对照组治疗的基础上联合体育疗法:举手展胸深呼吸动作,呼吸恢复运动。两组患者疗程均为10d。观察两组患者的临床疗效,临床症状缓解时间及不良反应发生情况。结果:治疗后试验组患者总有效率显著高于对照组,咳嗽减轻时间、喘息缓解时间、咳痰减少时间均显著低于对照组,两组比较差异均有统计学意义(P〈0.05)。两组患者治疗期间均未见明显不良反应发生。结论:常规药物联合体育疗法治疗慢性支气管炎疗效显著,安全性较好。OBJECTIVE: To observe clinical efficacy and safety of conventional drug combined with physical exercise therapy for chronic bronchitis. METHODS: 102 patients with chronic bronchitis were randomly divided into control group and trial group. Control group was given conventional treatment: antibiotics as amoxicillin 0.5 g, bid or roxithromycin 0.3 g, bid; antitussive and expectorant as Compound liquorice mixture 10 ml, rid and additionally giving bromhexine 8-16 rag, tid according to disease condition; relieving asthma as aminophylline 0.1 g, tid. Trial group was additionally given physical exercise based on control group: raising one's hand, expanding chest, breathing deeply; respiration recovery. Treatment course of 2 groups lasted for 10 d. Clinical efficacy, relieve time of clinical symptoms and the occurrence of ADR were observed in 2 groups. RESULTS : The total effective rate of trial group was significantly higher than that of control group, but relieve time of cough, wheeze and expectoration were significantly less than control group; there were statistical significance in 2 groups (P〈0.05). No obvious ADR was found in 2 groups. CONCLUSIONS : Conventional drug combined with physical exercise therapy is effective and safe for chronic bronchitis.
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