聚桂醇注射液与鱼肝油酸钠治疗食管静脉曲张的临床比较  

Clinical comparison of both lauromacrogol injection and sodium morrhuate in the treatment of esophagel varices

作　　者：陈坛辀[1] 林若阳[1] 韩清锡[1] 黄智铭[1] 

机构地区：[1]温州医科大学附属第一医院消化内科,浙江温州325000

出　　处：《中国内镜杂志》2014年第3期274-276,共3页China Journal of Endoscopy

摘　　要：目的探讨国产聚桂醇注射液与5%鱼肝油酸钠胃镜直视下注射治疗门静脉高压症食管静脉曲张破裂出血的临床疗效及副作用。方法 126例患者随机纳入试验组和对照组,患者各63例,分别应用聚桂醇注射液及5%鱼肝油酸钠在胃镜直视下对食管曲张静脉注射治疗。观察比较两组的急诊止血率、再发出血率、临床疗效及副作用。结果治疗后两组病人的急诊止血率、再发出血率和临床疗效无显著差异。聚桂醇注射液组副作用明显低于鱼肝油酸钠组。结论聚桂醇注射液是一种安全有效的硬化剂,与5%鱼肝油酸钠相比,其临床疗效无显著差异,而副作用发生率明显低于5%鱼肝油酸钠。【Objective】To explore the rate of emergency hemostasis, the rate of rebleeding and the clinical effects and side effects of both lauromacrogol injection and sodium morrhuate on portal hypertension in esophageal varies. 【Methods】126 patients were randomly divided into two groups. The test group of 63 cases was treated with lauromacrogol injection and the control group of 63 cases was treated with 5% sodium morrhuat. The clinical effects and side effects of the two drugs were studied. 【Results】No significant differences were found in terms of the rate of emergency hemostasis, the rate of rebleeding and clinical effects between the two groups. The occurrence rates of side effects in the group A were significantly lower than those in group B. 【Conclusion】Lauromacrogol injection is a safe and effective hardener. It has similar clinical effects to sodium morrhuate, while it has less side effects than sodium morrhuate.

关 键 词：聚桂醇注射液 鱼肝油酸钠 食管静脉曲张 

分 类 号：K768.31[历史地理—历史学]