阴沟肠杆菌肺炎的临床特点及药敏分析  

Enterobacter cloacae pneumonia:an analysis of clinical features and antibiotic susceptibility

作　　者：龚燕[1] 陆燕[1] 徐雯霞[1] 

机构地区：[1]上海瑞金医院卢湾分院老年科,上海200020

出　　处：《中国处方药》2014年第5期16-17,共2页Journal of China Prescription Drug

摘　　要：目的：分析和总结阴沟肠杆菌肺炎的临床特点和其对抗菌药物的敏感性的分布情况。方法对51例阴沟肠杆菌肺炎的临床资料进行统计分析，测定该菌的药物敏感性。结果阴沟肠杆菌肺炎多见于65岁以上老年患者（76.47%），其中多存在于低蛋白血症患者（60.78%）和患有基础疾病患者，如慢性阻塞性肺病（21.57%）、脑血管意外（27.45%）和糖尿病（33.33%）等。临床科室主要分布于老年科13例、外科7例和呼吸科6例，临床表现主要为咳嗽、咳痰51例（100%）。胸部X线均呈现程度不等的肺部浸润阴影。药敏检测表明，哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、美罗培南、帕尼培南、亚胺培南/西司他丁、阿米卡星、庆大霉素、妥布霉素比较敏感外（100%～66.67%），该菌广泛耐药。结论阴沟肠杆菌肺炎好发于老年、有基础疾病及免疫功能低下者，及早进行细菌药敏检测和选择可能敏感的抗菌药物可改善预后。Objective To analyze and summarize the clinical features and distribution of antibiotic susceptibility of Enterobacter cloacae pneumonia. Methods We statistically analyzed the clinical data of fifty-one cases of Enterobacter cloacae and determined drug susceptibility of this bactiria.Results 39 out of 51（76.47%）patients were elderly.100%patients were with underlying disease, while 11（21.57%）cases had chronic obstructive pulmonary disease history, 31（60.78%）cases were with hypoproteinaemia. Chest X-ray showed different-degree shadow on lungs. Besides panipenem、Imipenem and Cilastatin、cefoperazone and sulbactam、Amikacin、Piperacillin/tazo、Gentamicin、Meropenem、Tobramycin were susceptive（100-66.67%）, the drug susceptibility test showed,this bactiria were resistant to lots of antibiotics. Conclusion The risk factors of Enterobacter cloacae pneumonia were ageing, underlying diseases and immunodeficiency. Early drug sensitivity test and choosing susceptive antibiotics would improve the prognosis.

关 键 词：阴沟肠杆菌 肺炎 药物敏感性 

分 类 号：R446.5[医药卫生—诊断学]