丽水口岸出境人员鼠疫F1抗体阳性流行病学调查分析  

Analysis on results of plague F1 antibody positive among exit personnel at Lishui port

作　　者：麻慧君 傅圣勇 何晓翔 王彩书 蓝玉清[2] 梅建华[2] 石国祥[3] 

机构地区：[1]丽水出入境检验检疫局,浙江丽水323000 [2]丽水市疾病预防控制中心 [3]浙江省疾病预防控制中心

出　　处：《中国国境卫生检疫杂志》2014年第2期91-93,共3页Chinese Journal of Frontier Health and Quarantine

基　　金：浙江检验检疫局科研基金项目(ZK2008068X)

摘　　要：目的通过调查丽水口岸出境人员鼠疫F1抗体感染途径及其原因分析,掌握丽水口岸出境人员鼠疫F1抗体阳性人群分布情况。方法从2005年至2012年出境人员留样血清中,随机选择不同年龄的出境人员5 278份血清样本进行鼠疫Fl抗体间接血凝试验;对阳性者进行流行病学调查。结果 5 278份不同年龄的出境人员的血清样本中,采用间接血凝试验检测鼠疫Fl抗体,阳性样本3份,阳性率为0.057%。阳性者中,男性2例,女性1例;年龄最小58岁,最大74岁;对阳性者进行流行病学个案调查,除1例为历史鼠疫幸存者,其他均无明显的临床指征,但都有不同程度蚤类等叮咬史。结论人群血清中鼠疫F1抗体血凝阳性和鼠疫历史疫区有关,并在人血清中检获高滴度鼠疫F1抗体。F1抗体阳性者不一定是现患鼠疫病人,不一定存在传染性,但在鼠疫静息期加强鼠疫F1抗体监测,可对鼠疫感染起到预警作用。Objective According to the epidemiological investigation of appearance and cause of Lishui exit personnel with plague F1 antibody, and to master the population distribution of exit personnel with plague FI antibody positive at Lishui port. Methods A total of 5 278 serum were randomly selected for plague F1 antibody by IHA, which were from exit personnel of different ages during 2005 to 2012, and the epidemiological investigation was conducted in positive samples. Results Among the 5 278 sera of exit personnel from different ages by IHA are, three copies of plague F1 antibody were positive. In which, two cases were male and one case was female. The youngest person was 58 years old and the oldest was 74 years old. Except a plague survivor with a known history, others had no obvious clinical indications. However, they both had different degrees of biting history by fleas. Conclusion Plague F1 antibody-positive in human serum is relevant to the history of plague epidemic, and high titers in plague F1 antibody were seized in human serum. The F1 antibody-positive people are not or recent patients infected with plague bacteria, which do not exist with infectious immunity. To strengthen the monitoring plague F1 antibody during the plague resting period, which may play a role in early warning.

关 键 词：鼠疫 F1抗体 出境人员 流行病学 调查 分析 

分 类 号：R516.8[医药卫生—内科学]