甘肃省河西走廊地区2006-2010年夏秋季脑炎脑膜炎症候群病例调查  

Investigation of encephalitis and meningitis cases in Hexi corridor of Gansu province during summer and autumn from 2006 to 2010

作　　者：金娜[1] 董茂星[1] 王旭霞[1] 张晓曙[1] 李慧[1] 

机构地区：[1]甘肃省疾病预防控制中心,甘肃兰州730000

出　　处：《现代预防医学》2014年第10期1874-1877,共4页Modern Preventive Medicine

基　　金：中华预防医学会公共卫生应用研究与疫苗可预防疾病科研项目"甘肃省河西地区流行性乙型脑炎及相关病媒生物监测"(20102802)

摘　　要：目的分析甘肃省河西走廊地区2006-2010年夏秋季节脑炎脑膜炎症候群病例流行病学及临床特征,为河西走廊地区乙脑监测及防控策略提供理论依据。方法回顾性调查分析河西5市选取的8个市、区(县)辖区内县级及以上医院574例脑炎脑膜炎症候群病例。结果 574例脑炎脑膜炎症候群病例中以病毒性脑炎病例为主,占75.09%,15岁以下儿童发病最为常见,占44.60%,多见于学生、农民、幼托及散居儿童。脑炎脑膜炎症候群病例多急性起病,以轻型、中型为主;主要临床表现依次为头痛、恶心、精神萎靡、发热、呕吐及头晕,结核性脑膜炎患者头痛的发生率明显高于病毒性脑炎及化脓性脑炎患者,差异有统计学意义(P<0.05);化脓性脑膜炎患者精神神经症状的发生率明显高于病毒性脑炎及结核性脑膜炎,差异有统计学意义(P<0.05)。结论病毒性脑炎是河西走廊地区脑炎脑膜炎症候群的主要病种,结合历史数据,仍不能排除河西走廊地区存在乙脑病例的可能性。Objective The research was designed to analyze the epidemiological and clinical features of encephalitis and meningitis cases in Hexi corridor of Gansu province during summer and autumn season from 2006 to 2010. Utilizing historical data analysis, this study was aimed to provide theoretical basis for the control of the Japanese encephalitis （JE）. Methods Five hundred and seventy-four cases of encephalitis and meningitis were retrospectively surveyed and analyzed. Results Patients with viral encephalitis accounted for 75.09% of 574 cases with the syndromes of encephalitis and meningitis. Patients less than 15 years old took up 44.60% of all cases and the percentage for this age group was higher than other age groups. The majority of the patients were students, famers, and pre-school children. Most of the patients showed acute onset. The clinical classification was mild or moderate. The main clinical symptoms were headache, nausea, listlessness, pyrexia, vomiting, and dizziness. The headache incidence for patients with tuberculosis meningitis was significantly higher than patients with viral encephalitis or purulent meningitis （P〈0.05）, the incidence of neurological symptoms for patients with purulent meningitis was significantly higher than patients with viral encephalitis or tuberculosis meningitis. Conclusion Viral encephalitis was the major disease for the encephalitis and meningitis in Hexi corridor. Combining with history data, it is still difficult to draw the conclusion that there is no JE case in Hexi corridor of Gansu province.

关 键 词：脑炎脑膜炎症候群 河西走廊 病例调查 

分 类 号：R183.5[医药卫生—流行病学]