尿道淀粉样变性1例报告并系统文献复习  

Urethral amyloidosis:a case report and literature review

作　　者：陈书练[1] 付逆[1] 罗旭[1] 

机构地区：[1]遵义医学院附属医院泌尿外科,贵州遵义563099

出　　处：《现代泌尿外科杂志》2014年第5期322-324,共3页Journal of Modern Urology

摘　　要：目的总结尿道淀粉样变性(UA)的诊治经验,提高该病的诊疗水平。方法报道我院收治的1例UA患者,系统复习国内外相关文献,进行归纳和总结。结果 61岁男性患者,因排尿困难1年,加重3天就诊,尿道镜活检提示良性病变,剪开前尿道后于球部行人工尿道下裂术,术后病理确诊为尿道淀粉样变性,随访6个月,无复发。结论 UA为一种罕见的良性病变,根据临床表现常难以区分良、恶性,诊断依靠病理,并常需特殊染色。目前治疗意见尚不统一,应根据病程长短、患者症状、病变部位和程度、狭窄段长度等综合选择。Objective To summarize the diagnostic and therapeutic experience of urethral amyloidosis （UA）. Methods Data of one patient with UA treated in our department were reported and relevant literature was reviewed. Results A 61- year old male patient was hospitalized due to dysuria for one year and aggravation for three days. Transurethral endoscopic bi- opsy indicated a benign lesion. Hypospadia was performed on the bulbous urethra after an incision of the anterior urethra. Postoperative histopathological outcome indicated urethral arnyloidosis. A six-month follow-up identified no recurrence. Conclusions UA is a rare benign disease. It is difficult to identify the nature of the lesion through clinical manifestations. The diagnosis depends on histopathological examination and special staining. Treatment of UA is controversial. The course of the disease, symptoms, location and progress of lesions and the length of stricture should be taken into consideration.

关 键 词：尿道 淀粉样变性 组织病理学 

分 类 号：R695[医药卫生—泌尿科学]