早发冠心病不同性别患者临床危险因素和冠脉特点的对比研究  

Sexual Difference of Clinical Characteristics in Premature Coronary Heart Disease Patients

作　　者：马敏 刘云霞[2] 李洱花 叶吉云[2] 

机构地区：[1]昆明市延安医院心内科,云南昆明650101 [2]昆明医科大学,云南昆明650500

出　　处：《昆明医科大学学报》2014年第5期85-87,94,共4页Journal of Kunming Medical University

基　　金：云南省应用基础研究基金资助项目(2011FB150)

摘　　要：目的探讨早发冠心病患者冠心病危险因素和冠脉病变特点的性别差异.方法 260例经冠状动脉造影确诊的早发冠心病患者,男性130例,女性130例,对其血脂异常、糖尿病、抽烟、冠心病家族史、高血压和既往缺血性脑卒中史等危险因素和冠状动脉造影病变特点进行分析.结果在早发冠心病患者中,女性组高血压和糖尿病患病率明显高于男性组(P<0.05),而在男性组吸烟率明显增加(P<0.05).体重指数、高脂血症、既往脑卒中史和冠心病家族史在2组间未见显著差异(P>0.05).2组冠脉病变均以单支病变占优势(P<0.05),2组间冠脉病变特征无显著差异(P>0.05).结论在早发冠心病患者中,吸烟是男性患者的主要危险因素,而高血压病和糖尿病是女性患者的主要危险因素.两者冠脉病变特点无显著差异.Objective To analyze the sexual differences of clinical characteristics in premature coronary heart disease （PCHD） patients.Methods The clinical and coronary angiographic data were compared between male and female PCHDpatients （male ≤ 55 yearsold,n =130; female ≤ 65 yearsold,n =130） Results Compared with male PCHD patients,female patients had significantly higher prevalence rates of hypertension and diabetes （34.6％ vs 16.9％,27.9％ vs 15.3％,P ＜ 0.05） and lower smoking rate （6.0％ vs 65.4％,P ＜ 0.05）.There were no differences in BMI,hyperlipidemia,cerebral infarction and family history of coronary heart disease.There were more patients with single vessel lesion and no significantly differences of vessel lesions between two groups.Conclusion In PCHD patients,smoking was the main risk factor for male,while hypertension and diabetes for female.There were no significantly differences of vessel lesions between two groups.

关 键 词：早发冠心病 危险因素 冠脉病变特点 

分 类 号：R541.4[医药卫生—心血管疾病]