氢质子磁共振波谱在乳腺良恶性病变诊断中的价值探讨  被引量:2

Value of 1H-MRS in the diagnosis of breast lesions

在线阅读下载全文

作  者:荆彦平[1] 高峥嵘[1] 张俊[1] 南晓东[1] 辛欣[1] 张焱[2] 程敬亮[2] 

机构地区:[1]河南科技大学附属三门峡黄河医院MRI科,472000 [2]郑州大学第一附属医院磁共振科

出  处:《实用医学影像杂志》2014年第2期95-97,共3页Journal of Practical Medical Imaging

摘  要:目的:研究乳腺氢质子磁共振波谱(1H-MRS)的特点,评估其在鉴别乳腺良恶性病变中的价值。方法回顾性分析有明确病理结果且波谱采集成功的55个乳腺病灶(恶性37个、良性18个)及10个健康腺体的1H-MRS特点。结果37个恶性病灶中有28个在3.22×10^-6处出现胆碱(Cho)峰,9个未出现Cho峰;18个良性病灶有3个在3.22×10^-6处出现Cho峰,其他15个良性病灶和10个健康腺体都未出现Cho峰。以Cho峰鉴别良恶性病变的敏感度76%(28/37),特异度83%(15/18),阳性预测值90%(28/31),阴性预测值63%(15/24)。差异有统计学意义(Kappa=0.781,P<0.01)。1H-MRS阳性病例中,病灶最大径>2.5 cm占48%(15/31),2.0-2.5 cm占42%(13/31),1.5-2.0 cm为10%(3/31)。结论1H-MRS对乳腺肿瘤的敏感性及特异性较高,对病灶>1.5 cm的乳腺肿块性病变,可用1H-MRS协助鉴别病变的良恶性。Objective To study the features of breast proton magnetic resonance spectroscopy ( 1H-MRS), as-sessing its value on differentiating bengin from malignant lesions. Methods Retrospective analysis on 55 breast le-sions (37 malignant cases,18 benign cases) and 10 normal glands which had specific pathological results and spectral acquisition success, study the 1H-MRS features of them. Results Of 37 malignant lesions, Choline (Cho) peak ap-peared at 3.22×10^-6 in 28 items, 9 items didn′t have Cho peak;of 18 benign lesions, Cho peak appeared at 3.22×10^-6 in 3 items, the other 15 benign lesions and 10 normal glands didn′t obtain Cho peak. The sensitivity, specificity, pos-itive predictive value, negative predictive value of Cho peak on differentiate benign from malignant lesions was 76%(28/37), 83%(15/18), 90%(28/31), 63%(15/24) respectively, which had statistically significance (Kappa=0.781, P=0.000). The maximum diameters of positive 1H-MRS cases were 〉2.5 cm, 2.0-2.5 cm, and 1.5-2.0 cm, accounting for 48% (15/31), 42%(13/31) and 10%(3/31) respectively. Conclusion 1H-MRS have a relatively higher sensitivity and specificity for breast tumors, which can be used to help identify benign or malignant lesions for breast mass〉1.5 cm.

关 键 词:乳腺疾病 磁共振成像 磁共振波谱学 诊断 

分 类 号:R445.2[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象