低碳水化合物肠内营养对AECOPD血气分析及血清炎症因子的影响  

The effect of enteral nutrition support with low carbohydrate on blood gas analysis indexes and serum inflammatory factors of patients with AECOPD

作　　者：许衍硕 陈志斌[2] 李凡[2] 谢亦欢 叶国辉[1] 唐皓[2] 

机构地区：[1]东莞市石龙人民医院综合内科,523321 [2]中山大学附属第一医院普内科,广州510080

出　　处：《国际医药卫生导报》2014年第9期1215-1218,共4页International Medicine and Health Guidance News

基　　金：东莞市科技局科技计划项目（201310515000042）

摘　　要：目的 观察低碳水化合物肠内营养对AECOPD患者血气分析指标以及血清肿瘤坏死因子（TNF-α）、白介素-6（IL-6）、C反应蛋白（CRP）、人髓样分化因子（MyD88）的影响.方法 通过鼻饲管肠内给予AECOPD患者低碳水化合物肠内营养制剂,对照组采用正常营养匀浆制品.检测血气分析、IL-6、TNF-α、MyD88、CRP等指标.结果 治疗第7d与对照组比较,治疗组PaO2高于对照组,PaCO2、IL-6、TNF-α、MyD88、CRP水平均低于对照组,差异有统计学意义（P＜0.05）.结论 短期低碳水化合物肠内营养可改善AECOPD患者通气水平,并可以降低AECOPD患者炎症水平.Objective To observe effect of enteral nutrition support with low carbohydrate on blood gas analysis indexes and serum inflammatory factors of patients with AECOPD.Methods Patients in test group and control group were fed by nasal tube for 7 days,with low carbohydrate for test group and normal homogenate for control group.Detected and analyzed levels of blood gas analysis indexes,IL-6,TNF-α,MyD88 and CRP of patients in two groups.Results 7 days after treatment,the level of PaO2 in test group was higher than that in control group,the levels of PaCO2,IL-6,TNF-α,MyD88,CRP in test group were lower than those in control group,with statistically significant differences between two groups （P ＜ 0.05）.Conclusion Enteral nutrition support with low carbohydrate can improve ventilation function and reduce inflammation levels of patients with AECOPD.

关 键 词：低碳水化合物肠内营养 慢性阻塞性肺病急性加重期 血气分析 炎症因子 

分 类 号：R563.9[医药卫生—呼吸系统]