布拉氏酵母菌散联合蓝光治疗新生儿病理性黄疸临床疗效观察  

The clinical research on the effectiveness of Saccharomyces boulardii Sachets combined with blue-ray irradiation in neonatal pathological jaundice

作　　者：王智惠 王成秀[1] 李芳[2] 

机构地区：[1]重庆市第五人民医院儿科,重庆400062 [2]重庆医科大学附属儿童医院,重庆400014

出　　处：《西部医学》2014年第5期651-652,655,共3页Medical Journal of West China

摘　　要：目的观察布拉氏酵母菌散治疗新生儿病理性黄疸临床疗效。方法选取新生儿病理性黄疸106例,随机分为治疗组56例与对照组50例,两组均予常规治疗(蓝光光疗、补液、肝酶诱导),治疗组在常规治疗基础上加口服布拉氏酵母菌散剂,动态监测血清胆红素,并进行疗效比较。结果治疗组黄疸消退时间较对照组缩短,相同时间降低的程度大于对照组,且不良反应发生率下降,两组比较差异均有统计学意义(均P<0.01)。结论布拉氏酵母菌散治疗新生儿病理性黄疸疗效确切,副作用少,使用方法简便易行,值得临床推广应用。Objective To observe the clinical effectiveness of Saccharomyces boulardii Sachets combined with blueray irradiation in neonatal pathological jaundice.Methods 106 newborns with pathological jaundice were selected and randomly divided into two groups,in which treatment group with 56 cases and control group with 50 cases.Both groups were provided conventional therapy （Blue-ray Irradiation,fluid infusion,enzyme inducer）.Furthermore in the treatment group,Saccharomyces boulardii Sachets were added except of the conventional treatment.The level of bililubin and effectiveness were monitored in both groups.Results The shortened duration of pathological jaundice,the low level of bililubin at the same time point,the less side-effect was observed,and the difference was significant（P＜0.01）.Conclusion Saccharomyces boulardii Sachets combined with blue-ray irradiation is effective in neonatal pathological jaundice with little side-effect.

关 键 词：布拉氏酵母菌散 蓝光治疗 病理性黄疸 

分 类 号：R722[医药卫生—儿科]