硫酸钙球形颗粒牙槽骨修复材料的制备及性能研究  

Preparation and research of spherical particles of calcium sulfate for repairing alveolar bone defect

作　　者：伍小沛[1] 颜廷亭[1] 黄明华[1] 冷崇燕[1] 陈庆华[1] 

机构地区：[1]昆明理工大学材料科学与工程学院,昆明650093

出　　处：《化工新型材料》2014年第5期52-54,共3页New Chemical Materials

基　　金：云南省应用基础研究重点项目(2009CC020)

摘　　要：为改善硫酸钙球形颗粒牙槽骨修复材料的生物活性和降解性能,将硅酸钠水玻璃引入该材料中,α-半水硫酸钙为原料,采用搅拌法制备了硫酸钙球形颗粒。采用FT-IR,XRD,SEM表征材料的微观形貌,降解性能和生物活性。研究了水玻璃对材料结构与性能的影响。结果表明:水玻璃改变了硫酸钙球形颗粒表面的晶体结合;提高了其生物活性;随水玻璃浓度的增加,降解速度降低。水玻璃固化后在硫酸钙表面形成了Si-O网络膜,并含有大量Si-OH,从而起到了延缓降解速度和提高生物活性的作用。In order to improve the degradation and bioactivity properties of spherical particles of calcium sulfate,water glass was introduced in the materials.α-calcium sulfate hemihydrate was used as the raw materials to prepare spherical particles of calcium sulfate with stirring method.Microstructures,degradation and bioactivity of the materials were characterized by XRD,FT-IR and SEM,The effects of water glass on the structure and properties of the materials were analyzed. The results indicated that both the interface structure and surface crystal binding state of the particles were changed by the water glass,The bioactivity was significantly improved by the water glass,With increasing the concentration of water glass in the materials,the degradation rate of the materials was decreased,Si-O network membrane which contained a large number of Si-OH was formed on the surface of calcium sulfate,Therefore,the degradation rate was decreased and the bioactivity was significantly improved.

关 键 词：硫酸钙 球形颗粒 牙槽骨 水玻璃 

分 类 号：R318.08[医药卫生—生物医学工程]