Reconstruction of 3D light distribution produced by cylindrical diffuser in deep tissues based on photoacoustic imaging  

作　　者：谢文明 刘玉滨 李志芳 李晖 

机构地区：[1]Key Lab of OptoElectronic Science and Technology for Medicine [2]Fujian Provincial Key Lab of Photonic Technology [3]College of Photonic and Electronic Engineering, Fujian Normal University

出　　处：《Chinese Optics Letters》2014年第5期45-48,共4页中国光学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.61178089/81201124);in part by the Natural Science Foundation of Fujian Province(No.2011Y0019)

摘　　要：Measurement of light distribution in biological tissue contributes to selecting strategy and optimizing dose for biomedical application. In this letter, a photoacoustic method combined with Monte Carlo simulation was used to estimate the three-dimensional light distribution in biological tissue. The light distribution was produced by a cylindrical diffuser which interposed into tissues. The light profiles obtained by the method were compared to those detected by photo diodes. The experimental results demonstrate the feasibility of this method. The approach can play a significant role for photo-dosimetry in biomedical phototherapy.Measurement of light distribution in biological tissue contributes to selecting strategy and optimizing dose for biomedical application. In this letter, a photoacoustic method combined with Monte Carlo simulation was used to estimate the three-dimensional light distribution in biological tissue. The light distribution was produced by a cylindrical diffuser which interposed into tissues. The light profiles obtained by the method were compared to those detected by photo diodes. The experimental results demonstrate the feasibility of this method. The approach can play a significant role for photo-dosimetry in biomedical phototherapy.

关 键 词：Reconstruction of 3D light distribution produced by cylindrical diffuser in deep tissues based on photoacoustic imaging DEEP 

分 类 号：O439[机械工程—光学工程]