硅油基磁流体作为玻璃体腔填充物的力学特性  

An experimental study of silicone-based magnetic fluid implanted into the vitreous cavity

作　　者：龚雁[1] 王正才[2] 江依法[3] 陆樟献[4] 袁建树[1] 周行涛[5] 

机构地区：[1]宁波市第六医院眼科中心,315040 [2]宁波职业技术学院,315800 [3]浙江中医药大学信息技术学院,杭州310053 [4]浙江万里学院,宁波315101 [5]复旦大学附属眼耳鼻喉科医院眼科,上海200031

出　　处：《中华眼视光学与视觉科学杂志》2014年第3期173-176,共4页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：宁波市自然科学基金（2013A610258、2013A610051）

摘　　要：目的 从力学的角度探讨新型的硅油基Fe3O4磁流体作为玻璃体填充物的可行性.方法 实验力学研究.首先将硅油基Fe3O4磁流体在猪眼玻璃体腔内作为填充物进行了实验,观察了硅油基Fe3O4磁流体在磁场作用下在玻璃体腔内表面的运动特性.其次将硅油基Fe3O4磁流体填充到模拟眼球内,并将模拟眼球悬挂在梯度磁场中,测出该液体的作用力.结果 硅油基Fe3O4磁流体在巩膜壁内可随磁力线方向移动并聚集.测得硅油基Fe3O4磁流体作用于模拟眼球内壁的压力为17 mmHg.结论 该硅油基Fe3O4磁流体基本上符合玻璃体填充物的要求,并具有独特的移动及定位优点.为磁性液体应用于视网膜修复提供了初步的研究及应用价值.Objective This paper describes a new type of silicone-oil-based Fe3O4 magnetic liquid and discusses the feasibility of vitreous implants from the mechanics viewpoint.Methods This was an experimental study.The silicone-oil-based Fe3O4 magnetic liquid had been studied previously in the pig eye cavity.The experimental results demonstrated that the silicone-oil-based Fe3O4 magnetic liquid moves on the cavity surface and aggregates at some position under the action of the magnetic field force.The silicone-oil-based Fe3O4 magnetic liquid was filled into a simulated eyeball that was suspended in a gradient magnetic field.The force applied on the simulated eyeball was measured.Results The silicone-oil-based Fe3O4 magnetic liquid moved on the simulated eye cavity surface and aggregated along the magnetic field line with an applied pressure of about 17 mmHg.Conclusion The silicone-oil-based Fe3O4 magnetic liquid approximates the vitreous implant requirements,and has unique mobile and location advantages.This provides a preliminary study approach and an estimate of usefulness for magnetic liquid used in retinal repair.

关 键 词：填充物 玻璃体腔 硅油 磁流体 视网膜 

分 类 号：R774.1[医药卫生—眼科]