早期肾损害实验室诊断的研究进展  

The Research Progress in Laboratory Diagnosis of Early Renal Injury

作　　者：于秀娟[1] 欧超伟[1] 

机构地区：[1]广东医学院附属医院检验科,广东湛江524001

出　　处：《医学综述》2014年第8期1468-1470,共3页Medical Recapitulate

摘　　要：目前评估早期肾损害的金标准是尿微量白蛋白定量检测,该指标能在一定程度上反映肾脏损害,但并不能准确地反映肾功能的变化趋势。近年来,各种更为早期、稳定、准确的诊断指标,如胱抑素C、β2-微球蛋白、N-乙酰-β-D-氨基葡萄糖苷酶、中性粒细胞明胶酶相关脂质运载蛋白等逐渐成为研究的热点,与传统指标相比,其敏感性、特异性均大大提高。现对诊断早期肾损害的各项指标进行综述。Until now,the gold standard of assessing early renal damage is microalbuminuria quantitativedetection. The indicator can reflect the degree of kidney damage,but does not accurately reflect the trend of renal function. In recent years, the diagnostic indicators with the features of early stage, stability, and accuracy such as CystatinC, β2-microglobulin, N-acetyl-β-D-gluco-aminidase, neutrophil gelatinase-assoeiated lipoca1 lin and so on, have gradually become hotspots in the research field. Compared with the traditional indicators the sensitivity,specificity were greatly improved. Here is to make a review of the indicators of diagnosis of early renal damage.

关 键 词：高血压 糖尿病 系统性红斑狼疮 肿瘤 脑梗死 肾损害 研究进展 

分 类 号：R446.1[医药卫生—诊断学]