肠道微生态系统与肠黏膜免疫关系研究进展  

Correlation of gut microflora and intestinal mucosal immunity

作　　者：洪南[1] 湛先保[1] 

机构地区：[1]第二军医大学临床二队,上海200433

出　　处：《医学研究生学报》2014年第4期444-446,共3页Journal of Medical Postgraduates

摘　　要：肠道微生态系统参与肠黏膜免疫系统的发育,促进肠黏膜分泌型免疫球蛋白A(secreted IgA,sIgA)的合成,并与肠黏膜免疫细胞相互调节,是维持肠道稳态的重要机制,在炎症性肠病、肠易激综合征、小儿过敏性疾病等疾患的发生发展中发挥重要的作用。文中对肠道微生态系统与肠黏膜免疫功能关系的进展作一综述。Gut microflora , an important part in maintaining the intestinal homeostasis , can participate in the development of intestinal mucosal immune system , promote the synthesis of secreted IgA （ sIgA） and interact with intestinal immune cells .Gut micro-flora also plays a significant role in the development of inflammatory bowel diseases , irritable bowel syndrome , pediatric allergic disea-ses and other disorders .This paper reviews the advances about the correlation of gut microflora and intestinal mucosal immunity .

关 键 词：肠道微生态 肠黏膜 免疫 炎症性肠病 

分 类 号：R333.3[医药卫生—人体生理学]