拌种灵氨基酸衍生物的合成及其生物活性  

Synthesis and Bioactivity of Amino Acid Derivatives of Seedvax

作　　者：胡奎[1] 李俊凯[1] 赵阳 张旭[1] 杜铁钢[1] 方祖凯[1] 

机构地区：[1]长江大学农学院,湖北荆州434025

出　　处：《湖北农业科学》2014年第5期1061-1063,共3页Hubei Agricultural Sciences

基　　金：国家自然科学基金项目(31371976);国家大学生创新性实验计划项目(201210489327)

摘　　要：拌种灵四氢呋喃与乙醛酸乙酯或丙酮酸乙酯衍生合成出2个希夫碱化合物(Ⅰa和Ⅰb),经硼氢化钠还原合成2个拌种灵的氨基酸衍生物(Ⅱa和Ⅱb),并经熔点测定、NMR和MS表征。以拌种灵为对照药剂,测定了4个目标化合物对水稻纹枯病菌(Rhizoctonia solani)和水稻白叶枯病菌(Xanthomonas oryzae)的室内抑菌活性。结果表明4个目标化合物对水稻纹枯病菌和水稻白叶枯病菌均有抑菌活性。By derivative reaction of the seedvax and ethyl glyoxylate or ethyl pyruvate, 2 kinds of schiff base compounds（Ⅰ a-Ⅰb） were synthesized. Reduced by NaBH4, 2 kinds of amino acid derivatives of seedvax were synthesized（Ⅱa-Ⅱb）. The 4 target compounds were characterized by melting piont, NMR and MS, respectively. Using the seedvax as control, the in vitro bioactivities of the compounds to the Rhizoctonia solani and Xanthomonas oryzae were determined. The results showed that 4 target compounds could inhibit the growth against Rhizoctonia solani and Xanthomonas oryzae.

关 键 词：拌种灵 氨基酸衍生物 生物活性 

分 类 号：S482.2[农业科学—农药学]