多重耐药菌监测与临床分析  

Monitoring and Clinical Analysis of Multidrug-resistant Bacteria

作　　者：林梅[1] 肖一星[1] 杨碧霞[1] 张永忠[1] 

机构地区：[1]福建省龙岩市第二医院医院感染管理科,364000

出　　处：《医学理论与实践》2014年第10期1279-1280,1295,共3页The Journal of Medical Theory and Practice

摘　　要：目的:对多重耐药菌(MDROs)株的分离和耐药菌谱检测,为临床有效控制MDROs感染提供依据。方法:常规分离培养,鉴定菌种,并进行药敏试验,根据标准筛选MDROs并计算耐药率,同时追踪分析其易感因素。结果:195株多重耐药菌中主要为大肠埃希氏菌、肺炎克雷伯氏菌、鲍氏不动杆菌、金黄色葡萄球菌等4中病原菌,大部分耐>10种常用抗菌药物,其易感因素包括住院时间>2周、使用多种抗菌药物治疗以及多种有创操作和导管的留置。结论:多重耐药菌(MDROs)株对常用的抗菌药物几乎全部耐药,应高度重视抗菌药物合理使用,重视MDROs的预防隔离工作,加强监控。Objective：To provide reference for clinically effective control of multi-drug resistant organism（MDRO）infection trough isolation and detection of drug resistance spectrum of MDRO.Methods：Routine isolation and cultivation, identification of strains,and sensitivity test were performed and calculated according to the standard screening MDRO resistance rates,while tracking to analyze the predisposing factors.Results：Of 195strains of multi-resistant bacteria,the major pathogens were Escherichia coli,Klebsiella pneumoniae,Acinetobacter baumannii and Staphylococcus aureus 4 species of bacteria,most of which were resistant to more than 10commonly used antibiotics,and its predisposing factors included length of stay over 2weeks,using a variety of antibiotic treatment,and a variety of invasive operations and indwelling catheters.Conclusion：MDRO are resistant to almost all commonly used antibiotics,it should attach great importance to the rational use of antimicrobial agents,and it should pay attention to the prophylaxis and isolation of multidrug resistant strain.

关 键 词：多重耐药菌 耐药性 监测 

分 类 号：R978.1[医药卫生—药品]