MR扩散加权成像诊断前列腺癌的价值分析  

The value of magnetic resonance diffusion weighted imaging in the diagnosis of prostate cancer

作　　者：王利伟[1] 王牧[1] 王绍娟[2] 殷信道[1] 毛存南[1] 薛海林[1] 

机构地区：[1]南京医科大学附属南京医院(南京市第一医院)医学影像科,南京210006 [2]江苏省中医院CT室,南京210029

出　　处：《磁共振成像》2014年第3期198-201,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：南京医科大学科技发展基金(编号:08NMUM103)

摘　　要：目的评价MR扩散加权成像(DWI)在前列腺良、恶性病变鉴别诊断中的价值。材料与方法共47例患者进行MRI检查,其中良性前列腺增生29例,前列腺癌18例。检查方法包括常规T1WI、T2WI、DWI和脂肪抑制成像。所有病例经穿刺活检或手术证实。观察前列腺大小、病变位置、信号特点及肿瘤侵犯情况,对DWI、ADC数据行定量分析。结果 MRI显示18例恶性肿瘤患者中,发生于外周带13例,表现为T2WI外周带内结节状、片状异常低信号区;8例位于中央带或移行带。DWI对前列腺癌的诊断敏感度为81.07%、特异度为78.01%、准确率为80.11%。结论联合应用DWI成像方法可以提高MR对前列腺癌诊断的准确率。Objective：To evaluate diffusion weighted imaging （DWI） in the differential diagnosis of prostate benign and malignant lesions. Materials and Methods：Of 47 cases, 29 patients with benign prostatic hyperplasia and 18 cases of prostate cancer patients underwent magnetic resonance imaging check, scanning sequences included conventional T1WI, T2WI, DWI and fat suppression imaging. All cases were conifrmed by biopsy or surgery. Prostate size, lesion location, signal characteristics and tumor invasion situation were observed. The quantitative analysis of ADC and DWI was applied. Results：13 of 18 cases with prostatic cancer located in the peripheral zone, the performance were peripheral zone nodules, lfaky low signal area in T2WI;8 cases were in the central zone or transition zone. The sensitivity, speciifcity, accuracy rate of DWI for the diagnosis of prostate cancer were 81.07%, 78.01%,80.11%, separately. Conclusion：DWI can improve the accuracy rate of diagnosis of prostate cancer.

关 键 词：磁共振成像 前列腺肿瘤 前列腺增生 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]