多重耐药鲍曼不动杆菌感染危险因素分析  

Analysis of risk factors of infection induced by multidrug-resistant Acinetobacter baumannii

作　　者：赵凤容 陆水英[2] 张秀渝 黄长武[2] 陈维贤[2] 

机构地区：[1]重庆市酉阳县人民医院妇产科,409800 [2]重庆医科大学附属第二医院检验科,重庆400010

出　　处：《检验医学与临床》2014年第10期1310-1312,共3页Laboratory Medicine and Clinic

基　　金：国家"十二五"科学技术重大专项基金资助项目(2012ZX10004212003)

摘　　要：目的了解本地区多重耐药鲍曼不动杆菌感染的危险因素及耐药状况。方法回顾性分析80例多重耐药鲍曼不动杆菌患者与48例非多重耐药鲍曼不动杆菌感染患者的基本资料,以及菌株药敏试验检测结果;采用Logistic回归分析方法分析多重耐药菌株感染的独立危险因素。结果多重耐药鲍曼不动杆菌感染的独立危险因素包括入住重症监护病房(ICU)、侵入性操作、两种及其以上抗菌药物序贯使用或联合使用。多重耐药鲍曼不动杆菌对左氧氟沙星、氨苄西林/舒巴坦、亚胺培南、替卡西林/克拉维酸的耐药率均大于60%,对除上述4种药物以外抗菌药物的耐药率均超过90%。结论多重耐药鲍曼不动杆菌感染的独立危险因素包括入住ICU、侵入性操作、两种及其以上抗菌药物序贯使用或联合使用。严格进行医院环境的消毒和医院感染的监测,合理使用抗菌药物,是控制多重耐药鲍曼不动杆菌感染的重要手段。Objective To study the risk factors of infection induced by multidrug -resistant Acinetobacter baumannii .Methods Risk factors of infection of multidrug -resistant Acinetobacter baumannii were assessed by multivariate non -conditional logistic regression analysis .Results The independent risk factors leading to infections of multidrug -resistant Acinetobacter baumannii included hospitalization in Intensive Care Unit （ICU） ,using at least two kinds of antibiotic and invasive procedures .Conclusion Risk factors of multidrug -resistant Acinetobacter bau-mannii infection might include hospitalization in ICU ,invasive procedures and treatment of antibiotics ,and reasonable treatment could be very important .

关 键 词：多重耐药 鲍曼不动杆菌 独立危险因素 

分 类 号：R37[医药卫生—病原生物学]