腔内治疗35例糖尿病下肢动脉闭塞性病变的疗效观察  

Observation on the Efficacy of Endoluminal Therapy for 35 Diabetic Patients with Lower Ex- tremity Arterial Occlusive Disease

作　　者：杨昱[1] 于艳[1] 张雪冬[2] 

机构地区：[1]中国医科大学附属第一医院血管外科,辽宁沈阳110001 [2]阜新矿业集团总医院胸心血管外科,辽宁阜新123000

出　　处：《医学临床研究》2014年第4期659-662,共4页Journal of Clinical Research

摘　　要：【目的】探讨腔内治疗合并糖尿病的周围动脉闭塞性病变 （Peripheral Arterial Occlusive Disease,，PAOD）的疗效。【方法】回顾性分析35例伴发糖尿病的PAOD患者48次腔内治疗的临床资料。【结果】腔内操作技术成功率97．1％，术后30d无死亡病例。术前踝肱指数（0．419土0．142）显著低于术后（0．741±0．158），其差异有统计学意义（P〈0．01）；6个月、12个月、24个月及36个月的初次通畅率分别为85．2％、61．9％、54．3％及46．2％，二次通畅率分别为91．5％、83．1％、70．2％及63．3％，肢体保存率分别为94．3％、88．6％、85．8％及82．9％。【结论】经皮腔内治疗糖尿病PAOD具有通畅率较高、并发症少的优点，能较好地保持患肢的完整性。[Objective]To explore the efficacy of endoluminal therapy for diabetes mellitus with peripheral arterial occlusive disease（PAOD）. [Methods]Clinical data of 35 PAOD patients with diabetes mellitus treated by endoluminal therapy for 48 times were analyzed retrospectively. [Results] Endoluminal operation success rate was 97.1% 34/35）. No one died 30d after operation. Ankle/brachial index before operation was （0. 419 ±0. 142） which was markedly higher than that after operation（0. 741 ±0. 158）, and there was significant difference（ P d0. 001）. Primary patency rate at 6 months, 12 months, 24 months and 36 months was 85.2% ,61.9%, 54.3%, and 46.2% respectively, and. secondary potency rate was 91.5%, 83.1%, 70.2% and 63.3% respectively, and limb preservation rate was 94.3%, 88.6%, 85.8%and 82.9%, respectively. [Conclusion] Percutaneous endoluminal therapy for diabetic patients with PAOD has advantages such high patency and few complications, and can better remain the integrity of the affected limbs.

关 键 词：糖尿病并发症 动脉 下肢 

分 类 号：R587.1[医药卫生—内分泌]