糖尿病足介入治疗的疗效分析  

Analysis of the Efficacy of Interventional Treatment of Diabetic Foot

作　　者：莫建勋[1] 蒙雯雯[1] 叶烨[1] 唐盛发[1] 莫剑锋[1] 陈植涛[1] 莫春荣[1] 熊红[1] 杨灵红[1] 

机构地区：[1]中国人民解放军一八一医院内分泌科,广西桂林541002

出　　处：《医学临床研究》2014年第4期743-745,共3页Journal of Clinical Research

摘　　要：【目的】探讨使用血管内球囊扩张、支架植入等介入方法治疗糖尿病足（D F ）的临床疗效。【方法】35例DF患者，在控制血糖、调节血脂、扩张血管、控制感染和改善微循环等综合治疗基础上，对患侧相关动脉进行球囊扩张、支架植入等介入治疗，观察介入治疗后患肢的病情变化。【结果】所有患者介入操作均获成功，即时造影血流明显改善，未出现急性闭塞或血管破裂出血。治疗后5～7 d ，15例患者的症状得到明显改善；踝/肱指数（ABI）：由术前的0．52±0．16增加为0．95±0．25；趾/肱指数（TBI）：由术前的0．39±0．11增加为0．56±0．12。其中1例术后突发心梗死亡，1例发生血栓急性阻塞再次行介入治疗恢复；随访28例患者1年后再狭窄12例（42．9％）。【结论】对糖尿病足进行介入治疗能够有效的改善症状，延缓截肢时间，近期效果较好。但介入治疗的开展受多种因素的制约，须全面考虑选择适宜对象。[Objective] To explore clinical efficacy of interventional methods such as balloon dilation and stent placement for the treatment of diabetic foot .[Methods] Totally 35 patients with diabetic foot received interventional treatment such as balloon dilation and stent placement based on comprehensive treatment such as controlling blood glucose ,regulating lipid ,dilating blood vessels ,controlling infection and improving circula-tion .The condition changes of diseased limbs after interventional therapy were observed .[Results]All patients completed interventional therapy successfully .Immediate blood flow was improved obviously .No acute ob-struction or vascular rupture hemorrhage occurred .After the treatment for 5~7 days ,the symptoms of 15 pa-tients were relieved obviously .Ankle/brachial index（ABI） was （0 .95 ± 0 .25） ,while toe/brachial index（TBI） was （0 .56 ± 0 .12） .One patient died for postoperative sudden myocardial infarction .One patient recovered af-ter interventional therapy for acute thrombus occlusion .Among 28 patients followed up for 1 year ,12 patients （42 .9% ） had restenosis .[Conclusion] Interventional treatment for diabetic foot can effectively relief the symptoms ,delay amputation time .The short-term efficacy is good .But many kinds of factor can affect the us-age of interventional treatment .The choice of appropriate cases should be fully considered .

关 键 词：糖尿病足 治疗 

分 类 号：R587.2[医药卫生—内分泌]