支肺合剂联合西药对支原体肺炎患儿症状及体征的影响  

Effect of Zhifei Mixture Combined Western Drugs on Symptoms and Signs of Children with Mycoplasma Pneumonia

作　　者：姚艳青[1] 王子威[1] 丁瑛雪[1] 于洋[1] 蒋文星[1] 刘晓红[1] 张忠浩[1] 崔红[1] 

机构地区：[1]首都医科大学附属北京友谊医院儿科,北京100050

出　　处：《中国中西医结合杂志》2014年第5期522-525,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：北京市中医药科技项目(No.JJ2012-09)

摘　　要：目的观察支肺合剂Ⅰ号、Ⅱ号、Ⅲ号治疗三种证型支原体肺炎患儿主要、次要症状及体征的影响。方法将70例肺炎支原体肺炎患儿随机分为对照组(38例)和治疗组(32例)。两组均静脉滴注阿奇霉素,口服氨溴特罗口服溶液,治疗组根据辨证分型分别加服支肺合剂Ⅰ号、Ⅱ号、Ⅲ号。观察两组治疗前后主要、次要症状及体征(主要:发热、咳嗽、痰壅、气促、乏氧;次要:恶寒、心率、面色、精神、食欲、出汗)改善情况。结果病例脱落7例。与本组治疗前比较,两组治疗后主要、次要症状及体征评分均降低(P<0.01);对照组治疗后发热及咳嗽均明显改善(P<0.01),治疗组治疗后症状、体征均明显改善(P<0.01)。与对照组比较,治疗组治疗后主要症状及体征评分下降程度更大(P<0.01),患儿主要症状、体征改善更明显(P<0.05)。结论支肺合剂联合西药能显著改善支原体肺炎患儿主要及次要症状、体征,效果优于单用西药。Objective To observe the effect of three Chinese medical formulae （Zhifei Mixture I , Zhfei Mixture II, and Zhifei Mixture III） on main and secondary symptoms and signs of children with mycoplasma pneumonia in treating three types of children mycoplasma pneumonia. Methods Totally 70 children with mycoplasma pneumonia were assigned to the control group （38 cases） and the treatment group （32 case）. All patients were intravenously injected with Azithromycin and took Ambroxol Hydro-chloride and Clenbuterol Hydrochloride Oral Solution. Those in the treatment group additionally took Zhifei Mixture I , Zhfei Mixture II, and Zhifei Mixture Ill by syndrome typing. Their main and secondary symptoms and signs were observed before and after treatment （main symptoms and signs covered fever, cough, abundant sputum, short breath, and anoxia; secondary symptoms and signs covered aversion to cold, heart rate, facial complexion, spirit, appetite, and sweating）. Results Seven patients were lost in this study. Compared with before treatment in the same group, scores for main and secondary symptoms and signs decreased in the treatment group （P 〈0.01 ）. The therapeutic effect on fever and cough was obviously better in the control group （P 〈0.01 ）. The main and secondary symptoms and signs were more obviously improved in the treatment group than in the control group （P 〈0.01 ）. Commpared with the control group, scores for main and secondary symptoms and signs decreased more in the treatment group （P 〈0.01 ）. Patients＇ main and secondary symptoms and signs were more obviously improved （P 〈0.05）. Conclusions Zhifei Mixture combined Western drugs could significantly improve main and secondary symptoms and signs of mycoplasma pneumonia children patients. Its efficacy was superior to that of using Western medicine alone.

关 键 词：支肺合剂 支原体肺炎 症状 体征 

分 类 号：R725.6[医药卫生—儿科]