血清C反应蛋白在亚急性甲状腺炎诊断中的应用  

Application of serum C-reactive protein in the diagnosis of subacute thyroiditis

作　　者：崔焕焕[1] 李艳玲[1] 卢斌[1] 彭丽[1] 许一新[1] 王扬天[1] 李洁[1] 柏晓勇[1] 王坚[1] 

机构地区：[1]南方医科大学南京临床学院南京军区南京总医院内分泌科,210002

出　　处：《中华内分泌代谢杂志》2014年第5期414-416,共3页Chinese Journal of Endocrinology and Metabolism

摘　　要：探讨血清C反应蛋白（CRP）水平测定在亚急性甲状腺炎中的诊断价值。测定33例初诊的亚急性甲状腺炎患者和37例Graves病患者的血清CRP和红细胞沉降率（ESR）水平。亚急性甲状腺炎组的血清CRP水平较Graves病组更高（P〈0．01）。CRP的最佳诊断界点为7．14mg／L，且血清CRP与ESR水平显著相关（r=0．630，P〈0．01）。当亚急性甲状腺炎与Graves病鉴别有困难时，可考虑将血清CRP作为亚急性甲状腺炎的诊断标志物。The efficacy of serum C-reactive protein （CRP） in the diagnosis of subacute thyroiditis （SAT） was investigated. Serum CRP levels were determined at initial presentation of 33 subjects with SAT and 57 patients with Graves＇ disease. Erythrocyte sedimentation rate （ESR） was measured in all patients by Westergrens＇ method. The ESR and CRP levels were significantly higher in cases with SAT than in Graves＇ disease （ P 〈 0.01 ）. The best diagnostic cut-off point of CRP was 7.14 mg/L, and serum CRP level was correlated well with that of ESR （ r = 0. 630, P〈0.01 ）. This study highlights the scope of using serum CRP as a diagnostic marker of SAT, especially in situations when it seems to be confused with Graves＇ disease, a common cause of thyrotoxicosis.

关 键 词：C反应蛋白 格雷夫斯病 亚急性甲状腺炎 

分 类 号：R581.4[医药卫生—内分泌]