慢性阻塞性肺疾病呼吸衰竭患者合并上消化道出血的预后分析  

Prognostic Analysis of Chronic Obstructive Pulmonary Disease and Respiratory Failure Patients with Upper Gastrointestinal Bleeding

作　　者：陈培[1] 刘晓俊[1] 杨恂[1] 官和立[1] 高凌云[1] 

机构地区：[1]成都大学附属医院呼吸内科,成都610081

出　　处：《华西医学》2014年第5期897-899,共3页West China Medical Journal

基　　金：四川省卫生厅科研项目(110089)~~

摘　　要：目的探讨慢性阻塞性肺疾病(COPD)合并呼吸衰竭患者发生上消化道出血与近期预后的关系。方法回顾性分析2009年2月-2011年5月COPD合并呼吸衰竭患者73例,根据是否合并上消化道出血分为观察组与对照组,比较两组一般情况、好转率、病死率、平均住院时间以及心律失常发生率。结果观察组好转率低于对照组(P<0.001),病死率高于对照组(P<0.001),住院时间高于对照组(P<0.001),气管插管率高于对照组(P<0.05),心率失常发生率高于对照组(P<0.05)。结论上消化道出血是影响COPD合并呼吸衰竭患者近期预后的重要危险因素。Objective To investigate the relationship between chronic obstructive pulmonary disease （COPD） and respiratory failure in patients with upper gastrointestinal bleeding and recent prognosis. Methods We retrospectively analyzed the clinical data of 73 patients with COPD and respiratory failure treated from February 2009 to May 2011. The patients were assigned to the observing group （n=33） and control group （n=40）. General characteristics, improvement rates, mortality rates, lengths of hospital stay, endotracheal tube rates and arrhythmia rates were compared between the two groups. Results Age, sex, and medical history of the patients were similar in both groups （P 〉 0.05）. Compared with the control group, the improvement rate was lower （P 〈 0.001）, the mortality rate （P 〈 0.001）, length of hospital stay （P 〈 0.001）, endotracheal tube rate （P 〈 0.05） and arrhythmia rate （P 〈 0.05） were all higher in the observing group after treatment. Conclusion Upper gastrointestinal bleeding is a high risk factor for short-term prognosis patients with COPD and respiratory failure.

关 键 词：慢性阻塞性肺疾病 呼吸衰竭 上消化道出血 预防 

分 类 号：R563.9[医药卫生—呼吸系统]