生脉散合六味地黄丸治疗2型糖尿病气阴两虚证  

Shengmai Powder Combined Liuwei Dihuang Pills Applied in Treatment of Type Ⅱ Diabetes with Deficiency of Both Qi and Yin Syndrome

作　　者：邓小敏[1] 唐丽丽[1] 陆斌[1] 郭超峰[1] 

机构地区：[1]广西中医药大学第一附属医院,南宁530023

出　　处：《中国实验方剂学杂志》2014年第11期192-194,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广西壮族自治区中医药管理局科研课题(GZKZ1110)

摘　　要：目的:观察生脉散合六味地黄丸治疗2型糖尿病气阴两虚证的临床疗效。方法:选择80例2型糖尿病气阴两虚证患者,按随机数字表法分为治疗组和对照组,每组各40例,其中对照组采用口服西药降糖药或者注射胰岛素常规降血糖;治疗组在对照组治疗的基础上加服生脉散合六味地黄丸,治疗4周后观察比较两组的临床疗效。结果:①治疗组对气阴两虚中医证候的改善与对照组相比有显著性差异(P<0.05),治疗组优于对照组。②治疗后两组患者空腹血糖、餐后2 h血糖、糖化血红蛋白均有明显下降,均与组内治疗前比较有显著性差异(P<0.05),但两组间的改善比较差异没有显著性。结论:西医常规治疗联合生脉散合六味地黄丸在改善糖尿病患者口渴喜饮、体倦乏力、多食易饥、少气懒言等气阴两虚的特征性症状方面的作用优于单纯西医治疗,值得临床推广应用。Objective： To observe the clinical efficacy in the deficiency of both Qi and Yin syndrome of type Ⅱ diabetes by using Shengmai powder combined Liuwei Dihuang pills. Method： Eighty patients were randomly divided into a treatment group （40 cases） and a control group （40 cases）. Diabetes pills and insulin injection were used in both groups. But only give Shengmai powder combined Liuwei Dihuang pills to the treatment group. Then compare the clinical efficacy of two groups after a 4-week-course of treatment. Result： ①Treatment group had significant differences in the improvement of the deficiency of both Qi and Yin syndrome compared with the control group （P 〈0.05）. So treatment group was superior to the control group. ②The both groups patients＇ fasting blood glucose/postplandial 2 h blood sugar/glycated hemoglobin were all significantly decreased after the treatment, which had significantly differences compard with the prior treatment （P 〈 0.05）. However, there was no significance improvement comparison difference between the two groups. Conclusion： Conventional treatment combined Shengmai powder and Liuwei Dihuang pills has advantages in the amelioration of diabetics＇ characteristic of deficiency of both Qi and Yin syndrome such as hydrodipsia and desire for drinks, tired and debihtation, large food intake with rapid hungering, deficiency of Qi and disinclination to talk. So it is worth popularizing in clinical practice.

关 键 词：2型糖尿病 生脉散 六味地黄丸 气阴两虚证 

分 类 号：R287[医药卫生—中药学]