滋肾柔肝法对肾虚肝郁型早期先兆流产血清CA125的影响  

Influence of Zishen Rougan Method on Serum CA125 to the First-trimester Threatened Abortion with the Kidney Deficiency and Liver Depression Type

作　　者：赵薇[1] 陈霞[1] 詹群[1] 张利敏[2] 沈玮玮[2] 

机构地区：[1]南京市中医院妇科,江苏南京210001 [2]南京中医药大学,研究生江苏南京210029

出　　处：《四川中医》2014年第5期99-101,共3页Journal of Sichuan of Traditional Chinese Medicine

基　　金：江苏省中医药管理局资助(编号:HZ07036)

摘　　要：目的:在以往研究的基础上,进一步探讨肾虚肝郁型早期先兆流产时血清CA125的变化与妊娠结局的关系。方法:选择肾虚肝郁型早期先兆流产患者142例,随机分为中药治疗组72例和黄体酮对照组70例。动态观察两组治疗前后血清CA125水平的变化,并随访妊娠结局。结果:治疗组保胎成功率为81.94%,对照组78.57%,两组比较经统计分析无显著性差异。疗后两组患者血清CA125水平呈下降趋势,治疗组中治疗前后相比有显著性差异;组间各时段差异无统计学意义。但保胎成功组和失败组治疗前后各时段血清CA125水平无显著性差异﹙P>0.05﹚。结论:滋肾柔肝法治疗肾虚肝郁型早期先兆流产疗效显著。对孕妇血清CA125动态监测结果提示:本研究结果尚不能证实"孕妇早期血清CA125水平可以评估妊娠最终结局"的观点。Objective： On the past basis of clinical research, we further explored the change of serum CA125 for the firsttrimester threatened abortion with the deficiency kidney and depressed liver was connected with pregnancy outcome. Methods： 142 cases of the first-trimester threatened abortion women with deficiency of kidney and depressed liver were classified into two groups, the former as the traditional Chinese medicine treatment group （72patients） and the latter as progesterone controlled group （70 patients）. We dynamic observed the change of serum CA125, and follow pregnancy outcome. Results： The achievement ratio of tocolyis in treatment group was 81.94%, there was no significant statistical difference compared to the controlled group （78.57%）. Serum CAl25 of post-treatment offer downtrend, in treatment group, there was the significant statistical difference between prior treatment and post-treatment. In the interclass difference of each section was not statistically significant. But in succeed group and abortive group serum CA125 of each section between prior treatment and post-treatment was no significant statistical difference （ P〉0.05 ） . Conclusion ： The law of nourishing the kidney and liver has the significant effect in treating the first-trimester threatened abortion women with deficiency of kidney and depressed liver. This clinical research finding can not still acknowledge the viewpoint of ＂the first-trimester serum CA125 of gravida can evaluate the last gravidity sequelae＂.

关 键 词：先兆流产 滋肾柔肝法 血清CA125 妊娠结局治疗后 

分 类 号：R714.21[医药卫生—妇产科学]