滋阴补肾方治疗肾阴亏虚型帕金森病临床研究  

Yin Deficiency Type of Parkinson's Disease Clinical Studies Treatment of Kidney Yin

作　　者：王秀丽[1] 刘紫阳[2] 

机构地区：[1]陕西中医学院,陕西咸阳712046 [2]河南中医学院,河南郑州450046

出　　处：《中医学报》2014年第5期746-747,共2页Acta Chinese Medicine

摘　　要：目的:观察滋阴补肾方治疗肾阴亏虚型帕金森病临床疗效。方法:将58例患者按随机数字表法分为治疗组和对照组。对照组采用左旋多巴联合普拉克索治疗;治疗组在对照组治疗基础上加用滋阴补肾方治疗,连续治疗4个月,其中分别在治疗前、治疗后1个月、2个月和4个月采用《帕金森病功能评定量表》(UPDRS)与Webster评分量表分别评定疗效,观察临床疗效。结果:UPDRS与Webster评分标准情况下,组内比较,治疗组在治疗后1个月、2个月、4个月后的评分与治疗前比较差异均具有统计学意义(P<0.05),对照组在治疗后2个月及4个月评分与治疗前比较差异具有统计学意义(P<0.05);两组比较治疗2个月、4个月后差异有统计学意义(P<0.05)。疗效判定方面,使用UPDRS评分标准,两组比较差异有统计学意义(P<0.05)。Webster评分标准情况两组比较差异不具有统计学意义(P>0.05)。结论:滋阴补肾法治疗肾阴亏虚型帕金森病临床疗效显著。Objective：To observe the clinical efficacy of Nourishing Kidney-Yin in the treatment of Parkinson＇s disease of asthenia kidney yin. Methods ：58 subjects were divided into two groups randomly, and treatment group in which 30 cases were treated by nourishing kidney -Yin plus western medicine while control group in which 28 cases were given western medicine only. After 4 months treatment,UPDRS and Webster scores were collected to observed the clinical effect at four periods, the beginning, one month, two and four months after treatment. Results ： According to both UPDRS and Webster scores, for the intra-group comparison, statistically insignificance were performed （P 〈 0.05 ）after each three times treatment in treatment group while there were only statistically significance after two months and four months treatment（P 〈0.05） in comparison group. To the efficacy evaluation,compare to comparison group there was statistically significance （ P 〈 0.05 ） when we use Ridit method of analysis under UPDRS scores and no statistically significance （ P 〉 0.05 ） while Webster scores was used. Conclusion：Nourishing Kidney-Yin method is safe and effective for asthenia kidney yin Parkinson＇s disease.

关 键 词：帕金森病 肾阴亏虚证 滋阴补肾方 左旋多巴联合普拉克索 

分 类 号：R259.410.2[医药卫生—中西医结合]