右美托咪定和丙泊酚分别复合瑞芬太尼在小儿麻醉中维持喉罩通气的效果观察  

Dexmedetomidine and protocol were given remifentanil anesthesia in pediatric laryngeal mask airway to maintain the effect observed

作　　者：郑育娟[1] 张占东[1] 钱金洪[1] 

机构地区：[1]河北省唐山市妇幼保健院麻醉科,063000

出　　处：《山西医药杂志》2014年第9期1000-1002,共3页Shanxi Medical Journal

摘　　要：目的分析观察右美托咪定和丙泊酚分别复合瑞芬太尼在小儿麻醉中维持喉罩通气的临床效果。方法回顾性分析我院140例小手术患儿临床资料,按其用药不同分为2组,A组为右美托咪定复合瑞芬太尼麻醉用药;B组为丙泊酚复合瑞芬太尼用药。统计2组患者进入手术室时（T0）、诱导后（T1）、置入喉罩（T2）、手术结束（T3）、取出喉罩（T4）以及取出喉罩后20min时（T5）6个时间点的心率（HR）和脉搏血氧饱和度（SpO2）参数值,记录患者不良反应情况。结果 T5时,B组患儿HR显著低于A组（P〈0.05）,T1~T5时,B组患儿SpO2显著高于A组（P〈0.05）;B组患儿术中无手动通气案例,A组手动通气率为38.5%,差异有统计学意义（P〈0.05）;B组术后不良反应情况发生率为4.2%,A组为55.7%,差异有统计学意义（P〈0.05）。结论小儿手术麻醉药剂中丙泊酚复合瑞芬太尼维持喉罩通气效果显著优于右美托咪定复合瑞芬太尼,并且术后不良反应较少,值得临床推广。Objective To analyze the observed dexmedetomidine and protocol were given remifentanil anesthesia in pediatric laryngeal mask airway to maintain clinical effect. Methods A retrospective analysis of our hospital 140 cases of minor clinical data in children, according to their medication were divided into two groups. Group A of dexmedetomidine given remifentanil anesthetic; group B protocol and remifentanil medication. Statistical two groups of patients entering the operating room （T0）, after induction （T1）, placed LMA （T2）, end of surgery （T3）, remove the LMA （T4） and removed after 20 rain when the LMA （T5） six point in time, HR and SpO2 parameter values, adverse reactions were recorded. Results T5 when, group B was significantly lower than in children with HR in group A （P〈0.05）, T1-T5 when, SpO2 group B of children was significantly higher than in group A （P〈0.05）, children of group B were no manual ventilation case, group A of manual ventilation rate was 38.5 %, significantly different （P〈0.05）, group B, the incidence of postoperative adverse reactions 4.2 %, group A was 55.7%, the difference was significant （P〈0.05）. Conclusion Pediatric anesthesia drug protocol and remifentanil maintain laryngeal mask airway was better than dexmedetomidine given remifentanil and postoperative adverse reactions less worthy of promotion.

关 键 词：麻醉 儿童 二异丙酚 右美托咪定 瑞芬太尼 

分 类 号：R726.1[医药卫生—儿科]