深刺眶区穴位为主治疗年龄相关性黄斑变性的临床研究  

Clinical Study of Deep Needling at Orbital Points as Main Treatment for Age-related Macular Degeneration

作　　者：夏勇[1] 刘睿[2] 孙竞劲 辛世恩[3] 崔花顺[3] 刘世敏[1] 

机构地区：[1]上海中医药大学,上海201203 [2]复旦大学附属眼耳鼻喉科医院,上海200031 [3]上海中医药大学附属曙光医院,上海200021

出　　处：《上海针灸杂志》2014年第5期421-423,共3页Shanghai Journal of Acupuncture and Moxibustion

基　　金：上海市卫生局中医药科研基金(2010L001A)

摘　　要：目的观察深刺眶区穴位为主治疗年龄相关性黄斑变性的临床疗效。方法将47例年龄相关性黄斑变性(干性)患者(94只眼)随机分为3组,其中针刺组22例(44眼)、西药组15例(30眼)和空白对照组10例(20只眼)。针刺组取穴为睛明、上明、内瞳子髎、健明、承泣、球后等眶区穴位以及太冲。西药组给予维生素C 0.2 g和维生素E 0.1 g口服,每日3次。空白对照组门诊随访,不采取任何治疗措施。比较3组治疗前后最佳矫正视力及眼底照相、眼底荧光血管造影。结果针刺组治疗后最佳矫正视力与同组治疗前比较,差异无统计学意义(P>0.05)。西药组和空白对照组治疗后最佳矫正视力均下降,与同组治疗前比较,差异均具有统计学意义(P<0.05)。针刺组治疗后最佳矫正视力与西药组和空白对照组比较,差异均具有统计学意义(P<0.05)。针刺组经治疗后有32眼后极部黄斑区色素上皮萎缩减轻,色素紊乱消失,视网膜水肿明显减轻,未见新鲜出血或渗出。而西药组和空白对照组患者基本没有改善。结论针刺治疗年龄相关性黄斑变性具有较好疗效。Objective To investigate the clinical efficacy of deep needling at orbital points as main treatment for age-related macular degeneration. Methods Forty-seven patients （94 eyes） with age-related macular degeneration （dry） were randomly allocated to three groups： acupuncture group of 22 cases （44 eyes）, Western drug group of 15 cases （30 eyes） and blank control group of 10 cases （20 eyes）. For the acupuncture group selected were orbital points Jingming, Shangming, medial tongziliao, Jianming, Chengqi and Qiuhou, and point Taichong. The Western drug group received oral administration of vitamin C 0.2 g and vitamin E 0.1 g, three times a day. The blank control group was clinically followed up and not given any treatments. Best-corrected visual acuities, fundus photographs and fundus fluorescein angiograms were compared between the three groups before and after treatment. Results There was no statistically significant pre-/post-treatment difference in best-corrected visual acuity in the acupuncture group （P〉 0.05）. Best-corrected visual acuity decreased in both Western drug and blank control groups after treatment and there was a statistically significant pre-/post-treatment difference in the two groups （P〈0.01）. There was a statistically significant post-treatment difference in best-corrected visual acuity between the acupuncture group and the Western drug or blank control group （P〈0.05）. After treatment, the atrophy of macular pigment epithelia in the posterior pole of eyeball lightened, pigment disorders disappeared, retinal edema abated markedly and fresh bleeding or exudation was invisible in 32 eyes in the acupuncture group after treatment. However, they did not basically improve in the Western drug and blank control groups of patients after treatment. Conclusion Acupuncture has a better therapeutic effect on age-related macular degeneration.

关 键 词：针刺疗法 眶区穴位 黄斑变性 年龄相关性 

分 类 号：R246.82[医药卫生—针灸推拿学]