接触沥青筑路工人脂质过氧化水平调查  

Investigation on lipid peroxidation of road construction workers exposed to asphaltum

作　　者：涂程[1] 谭娟[2] 冉龙举[1] 

机构地区：[1]成都市疾病预防控制中心,四川成都610041 [2]成都市传染病医院,四川成都610061

出　　处：《现代预防医学》2014年第11期1970-1971,1974,共3页Modern Preventive Medicine

摘　　要：目的探讨接触沥青对筑路工人体内脂质过氧化水平的影响。方法测定直接接触沥青、间接接触沥青、非接触沥青工人血清中丙二醛(MDA)、总抗氧化能力(T-AOC)、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)的浓度或活性。结果两个接触组MDA含量均显著高于非接触组(P<0.05),T-AOC较非接触组明显降低(P<0.0001)。结论接触沥青的筑路工人存在脂质过氧化损伤,可能会影响到作业工人的健康。Objective To discuss lipid peroxidation of road construction workers exposed to asphaltum. Methods Among two exposed groups of road construction workers and the control group, indexes about lipid peroxidation such as MDA, T-AOC, SOD, GSH-Px, CAT were detected. Results The MDA concentration of the two exposed groups showed an significant increase compared with the control group （P〈0.05） and the T-AOC activity showed an significant decrease （P〈0.000 1）. Conclusion Asphaltum could cause lipid peroxidation damage, which may damage health of road construction workers.

关 键 词：调查 沥青 脂质过氧化 

分 类 号：R135[医药卫生—劳动卫生]