预防先天性佝偻病的早期新生儿骨碱性磷酸酶水平影响因素分析  

Correlative factors analysis on influencing bone alkaline phosphatase levels in congenital rickets prevention in newborns

作　　者：梁萍[1] 康华[1] 楼方[2] 

机构地区：[1]成都中医药大学护理学院,四川成都611137 [2]成都大学附属医院儿科,四川成都610000

出　　处：《现代预防医学》2014年第11期2004-2006,2011,共4页Modern Preventive Medicine

基　　金：四川省科技厅资助项目(2013JY0070)

摘　　要：目的检测早期新生儿骨碱性磷酸酶(BALP)活性,分析其与孕母妊娠期影响因素的相关性,为先天性佝偻病的早期干预提供理论依据。方法对246例早期新生儿进行骨碱性磷酸酶活性水平测定,应用多元回归模型,分析早期新生儿BALP活性水平与孕母妊娠期影响因素的相关性。结果早期新生儿出生胎龄、血清钙水平、母孕期保健和母亲文化程度4个因素对BALP活性水平有明显影响。结论做好孕母妊娠期保健工作是预防先天性佝偻病的关键,及时检测BALP,可起到早期防治的目的。Objective To investigate the correlative factors of influencing bone alkaline phosphatase （BALP） levels in congenital rickets prevention in newborns. Methods Measured bone alkaline phosphatase levels in 246 newborns, adopted multivariate regression model to analyze the correlation of BALP activity and influencing factors in pregnant women. Results The gestational age, serum calcium of newborns, health care during pregnancy and educational degree of pregnant woman were significantly related with the changes of BALP levels. Conclusion Preventing congenital rickets in newborns should start to grasp from antenatal care. Timely detection on BALP levels in newborns may enhance early diagnoses rate.

关 键 词：早期新生儿 骨碱性磷酸酶 先天性佝偻病 相关因素 

分 类 号：R174[医药卫生—妇幼卫生保健]