儿童流感嗜血杆菌感染分布及耐药性监测  

Distribution and drug resistance of the children haemophilus influenza

作　　者：叶满[1] 文晓君[1] 

机构地区：[1]广西医科大学第七附属医院,广西梧州543001

出　　处：《现代预防医学》2014年第11期2010-2011,共2页Modern Preventive Medicine

摘　　要：目的了解我院小儿患者感染流感嗜血杆菌的分布,动态观察其耐药性发展情况,为临床合理应用抗生素提供依据。方法采用回顾性方法统计分析2009-2012年我院流感嗜血杆菌的标本来源及耐药状况。结果我院小儿患者分离的流感嗜血杆菌呼吸道标本检出率最高(89.2%)。检出菌株对头孢噻肟未发现耐药;耐药率较低的抗生素分别为阿莫西林/棒酸15.6%,头孢呋辛23.2%,氯霉素22.3%。β-内酰胺酶检出率38.7%。结论我院患者流感嗜血杆菌感染以呼吸道为主。菌株对不同抗生素耐药性差异较大,应根据药敏结果合理选用抗菌药物。产β-内酰胺酶率较高,应引起重视。Objective To learn about the distribution of the children of haemophilus influenza in our hospital, to observe its development of drug resistance, and to provide basis for applying proper antibiotics therapeutically. Methods The samples of haemophilus influenza in our hospital from 2009 to 2012 and the drug resistance were analyzed using retrospective ways. Results The detection rate of the respiratory specimens with haemophilus influenza in the children patients in our school reached the highest rate of 89.2%. It had no drug resistance to cefotaxime. The drugs with the lowest drug resistance were Amoxicillin and Clavulanic acid （15.6%）, Cefuroxime （23.2%）, Chloramphenicol （22.3%）. It was 38.7% for β-lactamase. Conclusion The children patients of haemophilus influenza in our hospital are mainly infected due to the respiratory system. The bacterial strain has different drug resistance to different antibiotics. We should choose the antibacterial properly according to the drug resistance result. We should pay more attention to β -lactamase as it has higher drug resistance rate.

关 键 词：流感嗜血杆菌β-内酰胺酶 耐药性 

分 类 号：R179[医药卫生—妇幼卫生保健]