活性开环聚合制备pH响应性可降解聚酯  

Preparation of pH-Responsive Biodegradable Polyester by Ring-opening Polymerization

作　　者：路德待[1] 李娟[1] 段鹏雪 李婷娥 

机构地区：[1]西北师范大学化学化工学院,生态环境相关高分子材料教育部重点实验室,甘肃省高分子材料重点实验室,甘肃兰州730070

出　　处：《精细化工中间体》2014年第2期54-56,69,共4页Fine Chemical Intermediates

基　　金：国家自然科学基金青年基金项目(51103118)

摘　　要：分别以N-杂环卡宾有机催化剂和金属钠有机配合物作为活性催化剂催化单体3-[(苄氧羰基)甲基]-6-甲基-1,4-二氧六环-2,5-二酮进行开环聚合,解保护后得到具有pH响应性的聚(苹果酸-乳酸)共聚物。凝胶渗透色谱(GPC)和核磁共振(1H NMR)对聚合物的平均分子量及其结构测定的结果,2种催化剂都可以得到分子量分布较窄的聚合物,但N-杂环卡宾有机催化剂的单体转化率低。Ring-opening polymerization of 3-[（benzyloxycarbonyl）methyl]-6-methyl-1,4-dioxane-2,5-dione, which can be further converted into pH-responsive polyester after de-protection, was catalyzed separately by N- heterocyclic carbene and organo-sodium complexes. 1H NMR and GPC results showed that both catalysts could give the polymer with narrow molecular weight distribution, but the conversion of the monomer catalyzed by Nheterocyclic carbene was very low.

关 键 词：聚酯 PH响应性 可降解 开环聚合 

分 类 号：TQ323[化学工程—合成树脂塑料工业]