庚型肝炎传播途径及相关危险因素探讨  

STUDIES ON ROUTE OF TRANSMISSION AND RISK FACTORS OF HEPATITIS G.

作　　者：杨鲜平[1] 李应光[2] 

机构地区：[1]山东省泰安市中心医院,2710002 [2]泰安市卫生防疫站,271000

出　　处：《现代预防医学》2001年第1期1-3,共3页Modern Preventive Medicine

摘　　要：目的 :了解献血员中 HGV感染状况 ,探讨感染的危险因素以及是否存在输血之外的传播途径。方法 :采用EL ISA法和 RT- PCR法 ,对泰安市 189名无偿献血员、40 4名职业献血员、16 9名单采血浆献血员进行抗 - HGV和 HGVRNA检测 ;并对部分抗 - HGV阳性献血员及其家属进行流行病学调查。结果 :三种献血员人群抗 - HGV阳性率分别为 1.5 9% (3/189)、 0 .99% (4 / 40 4)和 5 .33% (9/ 16 9) ;HGVRNA阳性率分别为 0 %、 0 .2 5 % (1/ 40 4)和 2 .37% (4 / 16 9)。流行病学调查显示可能存在经母婴传播和性行为传播的感染者。结论 :单采血浆和不洁注射为感染危险因素 ;HGV有可能经母婴垂直和性行为传播。Objective:To understand the state of HGV infection,the route of transmission except blood transfusion and the risk factors in blood donors.Methods:Anti HGV and HGVRNA were tested by ELISA and reverse transcription polgmerase chain reaction for 189 volunteer blood donors,404 professional blood donors and 169 plasmapheresis blood donors in Taian City.Epidemiological survey was carried out in part of anti HGV positive blood donors and their relatives.Rusults:The positive rates of antibodies detected were 1 59%(3/189)、0 99(4/404) and 5 33%(9/169) respectively;the positive rates of HGVRNA were 0%、0 25%(1/404) and 2 37%(4/169) respectively.Mother to infant transmission in two persons infected and transmission of sexual behaviour in one person have been discovered.Conclusion:Poor sterilization in plasmapheresis and not clean injection history are risk factors of the infection;HGV infection may be transmitted by mother infant and sexual behaviour routes.

关 键 词：庚型肝炎 献血员 传播途径 危险因素 流行病学 

分 类 号：R512.601[医药卫生—内科学]