老年高血压病患者晨峰血压与动脉粥样硬化炎症因子相关性分析  

The correlation between morning blood pressure peak in patients with hypertension and atherosclerosis related inflammatory factors

作　　者：杜荣生[1] 李沂[1] 周传堃[1] 

机构地区：[1]成都大学附属医院心血管内科,成都市610081

出　　处：《临床合理用药杂志》2014年第14期8-9,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨晨峰血压(MBPS)与动脉粥样硬化相关炎症因子的相关性。方法将116例老年高血压病患者分为MBPS正常组(n=56)和MBPS异常组(n=60),测定患者动态血压及血浆动脉粥样硬化炎症因子水平,之后分析晨峰血压水平与各炎症因子之间的相关性。结果老年高血压病患者MBPS除与BMI、TC、TG、HDL-C等心血管危险因素相关外,MBPS与血清hs-CRP、TNF-α、MCP-1、MIF水平呈正相关。结论晨峰血压除与年龄、BMI、TC、TG、HDL-C等传统危险因素相关外,与血浆hs-CRP、TNF-α、MCP-1、MIF等动脉粥样硬化炎症因子也具有明显相关性。Objective To investigate into the correlation between morning blood pressure peak（MBPS）and athero-sclerosis related inflammatory factors in elderly patients with hypertension. Methods 116 cases of elderly hypertension were divided into MBPS normal group（n = 56）and MBPS abnormal group（n = 60）,measuring blood pressure variability and ath-erosclerosis related inflammatory factors in patients respectively. Then making an analysis of the relationship between morning blood pressure peak and atherosclerosis related inflammatory factors. Results In addition to age,BMI,TC,TG,HDL-C,MBPS was positively correlated with hs CRP、-TNF-α、MCP-1、MIF. Conclusion For elderly hypertensive patients,besides age, BMI,TC,TG,HDL-C,MBPS was positively correlated with atherosclerosis related inflammatory factors such as hs CRP、-TNF-α、MCP-1、MIF.

关 键 词：老年高血压病 晨峰血压 动脉粥样硬化 炎症因子 

分 类 号：R544.1[医药卫生—心血管疾病] R543.5[医药卫生—内科学]