东北地区军队离退休干部2型糖尿病血糖控制与治疗现状的调查研究  

Investigation into glycemic control and treatment of type 2 diabetes in the Northeast China army retired cadres

作　　者：李萍[1] 张绍维[2] 安伶[3] 韩洪波[4] 吴雁翔 王力[6] 王世伟[7] 张颖[1] 杨昕[1] 蒋丽敏[1] 邢雪[1] 彭蒙蒙[1] 梁琳琅[1] 

机构地区：[1]沈阳军区总医院内分泌科,辽宁沈阳110016 [2]解放军第202医院内分泌科,辽宁沈阳110005 [3]解放军第210医院内分泌科,辽宁大连116021 [4]解放军第208医院内分泌科,吉林长春130062 [5]解放军第463医院内分泌科,辽宁沈阳110042 [6]解放军第211医院内分泌科,黑龙江哈尔滨150080 [7]解放军第230医院内分泌科,辽宁丹东118000

出　　处：《临床军医杂志》2014年第5期495-499,502,共6页Clinical Journal of Medical Officers

摘　　要：目的了解东北地区军队离退休干部2型糖尿病血糖控制与治疗情况。方法采用问卷的形式调查。调查内容包括患者一般信息、糖尿病病程、HbA1c、空腹血糖、餐后2 h血糖、血压、血脂、肝功、肾功、血尿酸及治疗药物。结果受调查者中94.5%接受药物治疗。其中,37.9%单纯口服降糖药,24.1%单独应用胰岛素,29%接受口服降糖药联合胰岛素治疗,HbA1c的达标率分别为72.5%、54%、60.1%。口服降糖药中,1种降糖药(62.6%)和两种口服药联用(34.6%)方案比较常见;单药、2联用药、3联用药的达标率分别为78.1%,68.3%,100%。最常用的口服降糖药是阿卡波糖(35.3%),其次为二甲双胍(27.4%)、磺脲类降糖药(10.6%),格列奈类药物(9.6%)。联合2种口服降糖药最常用的方案是双胍类+阿卡波糖(34.0%)、格列奈类+阿卡波糖(22.6%)、双胍类+格列奈类(18.9%)。治疗者中91.8%至少有1种伴随疾病,74.4%有2种或2种以上伴随疾病。无论采取何种治疗方法,高血压病(71.6%)、血脂紊乱(27.9%)是最常见的2种伴随疾病,心血管疾病是最常见的慢性并发症(66.0%)。结论东北地区患2型糖尿病军队离退休干部血糖控制达标率明显高于国内调查水平,达到甚至高于国外糖尿病患者的调查结果。Objective To assess the blood glucose control and the treatment of type 2 diabetes mellitus （T2DM） in retired veteran cadres in Northeast Army of China. Methods In the questionnaire interview, general information of patients, medical history and complications for T2DM, laboratory investigations and treatment regimen were collected. Results There were 94.5% of patients who had been treated with drugs. Among all the treatment regimens, 37.9% of them were treated with oral antidiabetic drug （OAD） only,24. 1% treated with insulin only,and 29.0% with OAD and insulin. The target control rates of the three groups were 72.5% ,54.0% and 60.1% , respectively. Among all the OAD treatment regimens, one kind of OAD accounted for 62.6% and two kinds of OADs for 34.6%. The target control rates of one, two and three OAD（s） were 78.1% , 68.3% and 100% , respec- tively. The most frequently used OADs were acarbose （35.3%）, biguanides （27.4%）, sulphonylureas （ 10.6% ） and glinides （9.6%）. Among the combined regimens,34.0% were biguanide plus arearbose,22.6% were glinides plus aearbose, and 18.9% were biguanide plus glinides. Among all the patients,91.8% were complicated with at least one kind of concomitant disease, and 74.4% with at least two or more than two kinds of concomitant disease. Hypertension （71.6%） and dyslipidemia （27.9%） were the most common concomitant diseases under all treatment regimens. Cardiovascular disease （66.0%） was the most common chronic complication. Conclusion retired cadres with T2DM in the Northeast area is significantly better than that in the domestic survey.

关 键 词：2型糖尿病 离退休干部 HBA1C 口服降糖药 胰岛素 血糖控制 治疗方案 

分 类 号：R587.1[医药卫生—内分泌]