发热伴血小板减少综合征流行病学研究进展  

Research advances on epidemiology of severe fever with thrombocytopenia syndrome

作　　者：丁淑军[1,2] 林艺[2] 张晓梅[2] 王显军[2] 于学杰[1,3] 

机构地区：[1]山东大学公共卫生学院,济南251400 [2]山东省疾病预防控制中心,山东省传染病预防控制重点实验室,济南251400 [3]德克萨斯大学医学部,美国德克萨斯州77555-0609

出　　处：《中国人兽共患病学报》2014年第5期531-534,共4页Chinese Journal of Zoonoses

基　　金：国家自然科学青年基金项目(No.81102171);山东省卫生厅医药科技计划(No.2011HZ055);山东省科技发展计划(No.2012GHZ30031)联合资助~~

摘　　要：发热伴血小板减少综合征(Severe fever with thrombocytopenia syndrome,SFTS)是近几年来新发现的一种以发热伴血小板减少为主要临床表现的传染性疾病,新布尼亚病毒是引起该病的病原体。蜱叮咬是主要的传播途径,可通过人-人接触传播。该病发病急,病情进展快,部分患者可因多脏器功能衰竭而死亡,病死率约10%。本文对该病病原学、病例分布特点及其传染源、传播途径和易感人群三个流行环节方面的最新研究进展作一综述。Severe Fever with Thrombocytopenia Syndrome （SFTS） is an emerging infectious disease caused by SFTSV,a newly discovered bunyavirus.SFTS cases were first reported in 2006 and SFTSV was first isolated in 2009 in China.The disease has been reported in 16 provinces in eastern China,South Korea and Japan.SFTS is a hemorrhagic fever with major clinical manifestation of fever,gastrointestinal symptoms,thrombocytopenia and leucopenia.In severe SFTS patients,the clinical conditions may proceed quickly and result in multiple organ failure.The case fatality rate was approximately 10% in humans.The incidence rate of SFTS was significantly higher in middle age and old age people and fatal cases mainly occurred in elderly people.SFTSV is most likely to be transmitted by tick bite and it can also be transmitted from person to person.The animal amplify hosts of SFTSV include goat,dog,cattle and chicken.This article reviews the most recent advances on SFTS etiology,source of infection,distribution of SFTS cases,transmission route,and susceptible population.

关 键 词：发热伴血小板减少综合征 流行病学 宿主动物 传播媒介 

分 类 号：R373[医药卫生—病原生物学]