药学服务辅助干预儿童支气管哮喘管理效果的临床研究  

Clinical Study on Intervention Effects of Pharmaceutical Care on the Management of Children Bronchial Asthma

作　　者：魏理[1] 蒙晓[1] 刘亮辉[1] 于力[1] 陈爱欢[1] 

机构地区：[1]广州医科大学附属第一医院,广州510120

出　　处：《中国药房》2014年第22期2094-2096,共3页China Pharmacy

摘　　要：目的:制订并实施药学服务计划,探究其在儿童哮喘治疗过程中对肺功能情况和哮喘控制的影响,为药学服务计划进一步推广提供理论依据。方法:对2012年在我院儿科门诊确诊为支气管哮喘的儿童120例,按哮喘严重程度分为轻、中、重度,同等严重程度的患者随机分为试验组和对照组。试验组在常规治疗外给予药学服务干预,内容包括建立药历、患者教育、门诊咨询、生活指导、心理疏导和电话定期随访6个方面;对照组只接受常规治疗。6个月后采用独立样本t检验,对试验组和对照组患儿的肺功能指标[第1秒用力呼气容积占预计值百分比(FEV1%)和最大呼气流量占预计值百分比(PEF%)]、儿童哮喘控制测试(C-ACT)评分进行统计分析。结果:轻度患者中,与对照组相比,试验组FEV1%、PEF%和C-ACT评分均显著提高(t=2.07、2.34、2.52,P<0.05);中度患者中,与对照组相比,试验组FEV1%、PEF%和C-ACT评分均显著提高(t=2.34、2.83、2.99,P<0.05);重度患者中,与对照组相比,试验组FEV1%、PEF%和C-ACT评分均显著提高(t=2.41、2.07、2.38,P<0.05)。结论:药学服务干预儿童哮喘治疗,可有效改善患儿肺功能情况和哮喘控制水平。OBJECTIVE： To develop and implement pharmaceutical care plan, and to explore the influence of pharmaceutical care on pulmonary function and asthma control in children in order to provide theoretic evidence for further development of pharmaceutical care plan. METHODS： A total of 120 children who were diagnosed as bronchial asthma in our hospital during Jan. to Dec. in 2012 were divided into mild, moderate and severe groups, then they were randomly divided into experimental group and control group. The experimental group received not only routine treatment but also pharmaceutical care intervention, including the establishment of drug record, patient education, outpatient counseling, life guidance, psychological counseling and telephone follow-up for patients. The control group only received routine treatment. After six months, t-test of independent samples was conducted; the re- sults of pulmonary function index （FEVI% and PEF% ） and children asthma control test （C-ACT） were analyzed statistically. RE- SULTS： In mild asthma patients, FEVI%, PEF% and C-ACT score of experimental group were improved significantly, compared with control group （t=2.07, 2.34, 2.52,P〈0.05）; in moderate asthma patients, those of experimental group were improved significantly, compared with control group （t=2.34, 2.83, 2.99,P〈0.05）; in severe asthma patients, those of experimental group were improved significantly, compared with control group （t=2.41, 2.07, 2.38,P〈0.05）. CONCLUSIONS： Pharmaceutical care intervention can improve pulmonary function and asthma control in children with bronchial asthma.

关 键 词：药学服务 儿童 哮喘 肺功能 儿童哮喘控制测试 

分 类 号：R974[医药卫生—药品]