急性百草枯中毒患者早期并发症的特点及其影响预后的临床研究  

Clinical Study on the Characteristics of Early Complications in Patients with Acute Paraquat Poisoning and Influence the Prognosis

作　　者：熊念芬 吴玄生 邹维武 尹杨光 江玉[3] 

机构地区：[1]重庆市永川区中医院急诊科,重庆402160 [2]第三军医大学第二附属医院急诊科,重庆402160 [3]泸州医学院附属中医院,四川泸州646000

出　　处：《现代生物医学进展》2014年第12期2335-2338,共4页Progress in Modern Biomedicine

基　　金：四川省教育厅项目(11ZB130)

摘　　要：目的:探讨分析急性百草枯中毒患者早期并发症的特点及其影响预后因素。方法:对我院收治的87例急性百草枯中毒患者的临床资料进行回顾性分析,并按照是否中毒死亡,分成死亡组与存活组,检验并对比分析两组患者并发症发生率差别。结果:77例患者早期出现并发症状,发生率为88.51%,其中凝血功能障碍发生率最高,占52.9%;死亡组患者与存活组患者在肝功能障碍、凝血功能障碍、呼吸功能损害、胰腺功能障碍以及肌肉损害等并发症发生率对比,差异具有统计学意义(P<0.05)。结论:急性百草枯中毒患者具有较高的死亡率,应在早期关注患者出现的各种并发症症状,采取有效措施预防与治疗肝功能障碍、凝血功能障碍、呼吸功能损害、胰腺功能障碍以及肌肉损害等症状,有利于改善患者预后情况,值得临床进一步研究与探讨。Objective：To analyze the risk factors of clinical medication by means of detecting and inspecting the safe use behaviors of drugs in our hospital,and to explore the probable measures to strength the pharmaceutical risk management so that the security risks of the usage for drugs could be prevented.Methods：Patients that from major department in our hospital were selected to take the investigation on the medication,and the hospital staff that from the representative sections were surveyed and evaluated by the＂Hospital Drug Safety Monitoring and Evaluation＂in terms of the drug risk warning and associated factors assessment.Then the investigative results were collected and analyzed.Results：The proportion of risk factors：Doctors,30.50%;Pharmacists,9.00%.Nurses,32.00%;Patients,28.50%.There were 83.3% people that have the knowledge of health care of clinical medicine,but only 50.6% of the staff have the conscious of taking basic precautions.Medication risk warning survey has showed us that the PASS warning effective rate was 57.5%;the highest incidence that from patients was 55.16%.External factors followed by 31.29%.Drugs were account for 26.95%.Conclusion：In order to prevent the incidence of drug risks,patients should take care of medication safety,medical institutions should strengthen the management of clinical medicine,identify and analyze the risks,strengthen the awareness and knowledge of the rational use of drugs as well as make efforts to build a system for medicine control,to create a good medical safety atmosphere for the pharmaceutical field.

关 键 词：急性 百草枯中毒 早期并发症 预后 影响因素 

分 类 号：R595.4[医药卫生—内科学]