一测多评中药质量控制研究进展  

Advance in quality control for traditional Chinese medicines by QAMS

作　　者：郭东晓[1] 林永强[1] 林林[1] 汪冰[1] 徐丽华[1] 

机构地区：[1]山东省食品药品检验所,山东济南250101

出　　处：《药学研究》2013年第9期530-533,538,共5页Journal of Pharmaceutical Research

摘　　要：一测多评(QAMS)是近年来新兴的中药质量控制方法,能够在缺少对照品的情况下实现多成分质量控制。迄今,QAMS报道的中药材、饮片以及中药制剂已达数十种。植物次级代谢产物是多数中药发挥药效作用的物质基础,也是评价相应中药质量优劣的关键。本文从植物次级代谢产物的角度,综述了近年来QAMS在中药质量评价中的研究进展,为该方法进一步的研究和应用提供了参考。In recent years, QAMS has been a burgeoning quality control method for traditional Chinese medicines （ TC- Ms）. The content of several compounds could be determined together with only one reference substance by the aforemen- tioned method. So far,the method had been applied in quality evaluation of dozens of TCMs. Most of TCMs took effect based on the activities of secondary metabolites they contained. Therefore, the secondary metabolite is crucial in the quality control of corresponding TCMs. From the aspect of secondary metabolite, this essay reviewed the progress of QAMS, which also pro- vided references for further development and application of the method.

关 键 词：一测多评 次级代谢产物 质量控制 中药 

分 类 号：R284[医药卫生—中药学]