小儿社区获得性肺炎的致病菌分布及耐药性分析  

Pathogen distribution and drug resistance analysis of community-acquired pneumonia in children

作　　者：陈紫桃 易燕桃 李迪[1] 余燕红[1] 陈影[1] 陈尚良 

机构地区：[1]广东省肇庆市第二人民医院药剂科,广东肇庆526060 [2]广东省肇庆市中心血站检验科,广东肇庆526020

出　　处：《中国当代医药》2014年第15期107-109,共3页China Modern Medicine

基　　金：广东省肇庆市科技创新计划项目(2013E2815)

摘　　要：目的探讨小儿社区获得性肺炎致病菌分布情况,并分析其耐药性。方法选择小儿社区获得性肺炎453例,留取痰标本送病原学检测后,明确主要致病菌分布情况,并总结最常见致病菌(本组为肺炎链球菌)对不同抗菌药物的敏感性。结果本组453例患儿肺炎链球菌感染者显著多于流感嗜血杆菌、金黄色葡萄球菌、表皮葡萄球菌、肺炎克雷伯菌(P<0.05)。316例肺炎链球菌感染者,对四环素和红霉素耐药性最高,对万古霉素和头孢呋辛敏感性最高,对青霉素耐药性高于头孢噻肟(P<0.05)。结论针对社区获得性肺炎患儿,经验用药应用头孢呋辛治疗,一般能取得较好的临床效果。Objective To investigate the pathogen distribution and drug resistance of community-acquired pneumonia in children. Methods 453 cases with pediatric community-acquired pneumonia,all were sent to sputum specimens the etiology of post-test to clear the case of the distribution of the main pathogens,and all were summarized the most com- mon pathogens （Streptococcus pneumoniae in this group） to different antimicrobial susceptibility. Results 453 eases in- fected by Streptococcus pneumoniae were more than Haernophilus influenzae,Staphylococcus aureus,Staphylococcus epidermidis,Klebsiellapneumoniae （P〈0.05）.316 cases of Streptococcus pneumoniae were highest resistant to tetracy- cline and erythromyein,highest sensitive to vancomycin and cefuroxime,the resistance to penicillin was higher than cefo- taxime （P〈0.05）. Condttsion For community-acquired pneumonia in children,experience drug use cefuroxime therapy earl generally achieve better clinical results.

关 键 词：小儿 社区获得性肺炎 致病菌 耐药性 

分 类 号：R563.1[医药卫生—呼吸系统]