舒芬太尼对罗哌卡因神经阻滞作用的影响  被引量:5

Effect of sufentanil on action of ropivacaine

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作  者:张大志[1] 刘永盛 周海滨[1] 王怀江[1] 

机构地区:[1]北京积水潭医院麻醉科,100035 [2]广州仁爱集团仁爱医院麻醉科

出  处:《中华临床医师杂志(电子版)》2013年第3期92-94,共3页Chinese Journal of Clinicians(Electronic Edition)

摘  要:目的比较舒芬太尼复合罗哌卡因神经阻滞对罗哌卡因阻滞时效的影响。方法 60例患者随机分为Ⅰ、Ⅱ两组,每组30例。所有患者均在神经刺激器定位下行坐骨神经复合腰丛阻滞麻醉。Ⅰ组:1%罗哌卡因200mg加入生理盐水30ml;Ⅱ组:1%罗哌卡因200mg加入舒芬太尼20μg(2ml)、生理盐水28ml。结果Ⅰ组患者感觉阻滞持续时间和运动阻滞持续时间[腰丛(7.9±3.6)h和(5.9±3.4)h、坐骨神经(8.2±3.5)h和(6.6±3.2)h]明显短于Ⅱ组[腰丛(15.1±2.4)h和(10.2±3.5)h、坐骨神经(16.3±2.7)h和(11.7±3.8)h](P<0.01)。Ⅰ组患者48h舒芬太尼的消耗量、按压总次数和有效次数比Ⅱ组多(P<0.05)。结论 0.4μg/ml的舒芬太尼能明显延长0.4%罗哌卡因腰丛-坐骨神经阻滞作用时间,减少术后阿片类药物的使用。Objective To compare effect of sufentanil on the action of ropivacaine.Methods Sixty patients were randomly allocated into two groups with 30 cases each.Guided by a nerve stimulator,lumbar plexus combined sciatic nerve block was performed with 1% ropivacaine 200 mg plus normal saline (NS) 30 ml in group Ⅰ,1%ropivacaine 200 mg plus sufentani120 iμg(2 ml) and normal saline (NS) 28 ml in group Ⅱ.Results The durations of sensory and motor blockade in group Ⅰ [lumbar plexus(7.9 +3.6)h and (5.9 +3.4) h,sciatic nerve(8.2 ±3.5)h and (6.6 ± 3.2) h] were significantly shorter than in group Ⅱ [(15.1 ± 2.4) h and (10.2 ± 3.5) h,(16.3 ± 2.7)h and(11.7 ± 3.8)h] (P < 0.01).The postoperative sufentanil consumption and PCA button press times in group Ⅰ were more than that of group Ⅱ (P < 0.05) at 48 h after operation.Conclusions Sufentanil 0.4 μg/ml significantly prolonged the action of ropivacaine in lumbar plexus combined sciatic nerve block and decreased the consumption of opiods for postoperative controlled analgesia.

关 键 词:罗哌卡因 舒芬太尼 神经传导阻滞 

分 类 号:R614[医药卫生—麻醉学]

 

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