白塞病55例临床分析  

Clinical Analysis of 55 Cases of Behcet's Disease

作　　者：史文毅[1] 王旭东[1] 曲才杰[2] 曲岩磊[2] 

机构地区：[1]青岛市市立医院口腔科,山东青岛266011 [2]青岛市市立医院皮肤科,山东青岛266011

出　　处：《中国皮肤性病学杂志》2014年第6期579-580,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的分析白塞病的临床特征,减少临床医生的误诊率和漏诊率。方法对2008年1月-2013年7月本院口腔科和皮肤科确诊的55例白塞病患者临床资料进行回顾性分析。结果男∶女为1.29∶1;平均发病年龄(31.22±11.37)岁;平均病程(2.50±1.86)年。最常见的临床表现为口腔溃疡(98.18%),其次为生殖器溃疡(70.91%)、针刺反应阳性(69.09%)、发热(38.18%)、关节炎(36.36%)、结节性红斑(34.55%)、假性毛囊炎(30.91%)和眼损害(29.09%)。实验室检查异常包括血沉增快(56.36%),白细胞计数升高(38.18%),IgG升高(36.36%),C反应蛋白升高(32.73%),中性粒细胞百分比升高(27.27%),IgM升高(20.00%)。结论白塞病的临床表现多样,可累及多器官和多系统,其实验室检查结果和组织病理学表现缺乏特异性,诊断主要依靠临床表现。Objective To study the clinical features of Behcet＇s disease in order to minimize the misdiagnosis and missed diagnosis rates. Methods The clinical data of 55 cases of Behcet＇s disease from department of stomatology and dermatology of our hospital from January 2008 to July 2013 were retrospectively analyzed. Results The ratios of male/female weere 1.29： 1. The average age at onset of Behcet＇s disease was 31.22 ± 11.37 years. The mean duration was 2.50 ± 1.86 years. The most common clinical manifestation was oral aphthosis （ 98.18 % ）, followed by genital aphthosis （ 70.91% ）, positive patbergy test （69. 09% ）, fever （38.18%） ,arthritis（36. 36% ）, erythema nodosum（34. 55% ） ,pseudofolliculitis （30. 91% ） and ophthalmologic lesions （29.09%）. laboratory abnormalities included an elevated erythrocyte sedimentation rate（56. 36% ） ,leukocytosis （38. 18% ）, an elevated IgG level （36.36%）, an elevated C reactive protein level （ 32.73% ）, neutrophilia（27.27% ）and an elevated IgM level（20. 00% ）. Condusion Multiple organs and systems could be involved in Behcet＇s disease with diversity of clinical manifestations. There were no specific laboratory and histopathology findings and Behcet＇s disease should be diagnosed mainly by clinical manifestations.

关 键 词：白塞病 临床分析 

分 类 号：R593.2[医药卫生—内科学]