儿童继发性骨质疏松症病因学研究进展  

Research progress of the etiology of the secondary osteoporosis in children

作　　者：史强[1] 李旭[1] 

机构地区：[1]南方医科大学第三附属医院儿童骨科,广州510630

出　　处：《中国骨质疏松杂志》2014年第5期584-588,共5页Chinese Journal of Osteoporosis

摘　　要：骨质疏松症通常被认为是一个影响成人的全球性公共健康问题。然而,儿童骨质疏松症,却是一种新的和不断变化的领域,具有一定独特的诊断和临床挑战。伴随诊断和治疗技术的发展,人们对儿童骨质疏松症的认识渐深入,特别是由各种疾病、药物等引起的儿童继发性骨质疏松症更加引起关注。儿童不是成人的缩影,很多疾病不能仅仅按照成人的方法进行诊断治疗。导致儿童继发性骨质疏松的主要因素包括:运动负荷减少、炎症因子、糖皮质激素、青春期紊乱与营养不良、儿科疾病与器官移植等疾病。为了加强人们对发生在儿童时期继发性骨质疏松症的认识和预防,本文对近年来儿童继发性骨质疏松的定义、诊断和相关影响因素展开综述。Osteoporosis is generally identified as a global public health problem affecting adults.However, osteoporosis in children is a new and evolving field, with certain unique diagnostic and clinical challenges.With the development in diagnosis and treatment, more deep understanding of the secondary osteoporosis in children has been acquired, especially about those caused by various diseases, drugs, etc.Children are not the miniature of adults.Thus, many diseases in children cannot be diagnosed and treated according to the methods in adults.The main factors leading to the secondary osteoporosis in children include the decrease of exercise loading, inflammation factors, glucocorticoid, adolescent disorders and malnutrition, pediatric diseases, and organ transplantation.In order to strengthen the awareness and the prevention of the secondary osteoporosis in childhood, this paper reviews the definition, diagnosis, and related factors of the secondary osteoporosis in children in recent years.The secondary osteoporosis in children is a new research field in the study of osteoporosis.To establish the controlled, randomized, and double-blinded trial about children, which can be used to confirm the etiology of osteoporosis in children and to evaluate the fracture risk, is the main direction of further study.

关 键 词：继发性骨质疏松 病因学 儿童 

分 类 号：R68[医药卫生—骨科学]