An effective amperometric biosensor based on graphene modified gold nanowire arrays for glucose detection  

作　　者：Jianing Hui Jiewu Cui Lingjuan Liu Guangqing Xu Yucheng Wu 

机构地区：[1]Laboratory of Functional Nanomaterials and Devices,School of Materials Science and Engineering,Hefei University of Technology [2]Key Laboratory of Advanced Functional Materials and Devices of Anhui Province

出　　处：《Chinese Science Bulletin》2014年第17期2012-2016,共5页

基　　金：supported by the National Natural Science Foundation of China (91023030,51072044,51102071,51172059,and 51272063);the International Scientific and Technological Cooperation Project of Anhui Province (10080703017)

摘　　要：A novel glucose biosensor based on graphene nanosheets(GNs)modified gold nanowire arrays(AuNWAs)electrode was constructed.Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates.GNs were synthesized through a public route involving graphite oxidation,exfoliation,and chemical reduction.Field emission scanning electron microscope and high-resolution transmission electron microscope were employed to characterize the asprepared AuNWAs and GNs.Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method.The cyclic voltammetry results showed that the GNs-AuNWAs-based glucose biosensors have high catalysis activity to hydrogen peroxide(H2O2)than those modified with GNs or AuNWAs only.Furthermore,amperometric response was employed to detect glucose concentration owing to its simplicity,high selectivity,and relative low cost.Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sensitivity of 40.25 lA cm-2(mmol/L)-1,low detection limit of 0.02 mmol/L,and a linear range from 0.02 to 3 mmol/L.A novel glucose biosensor based on graphene nanosheets （GNs） modified gold nanowire arrays （AuN- WAs） electrode was constructed. Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates. GNs were synthe- sized through a public route involving graphite oxidation, exfoliation, and chemical reduction. Field emission scan- ning electron microscope and high-resolution transmission electron microscope were employed to characterize the as- prepared AuNWAs and GNs. Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method. The cyclic voltam- metry results showed that the GNs-AuNWAs-based glu- cose biosensors have high catalysis activity to hydrogen peroxide （H2O2） than those modified with GNs or AuN- WAs only. Furthermore, amperometric response was employed to detect glucose concentration owing to its simplicity, high selectivity, and relative low cost. Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sen- sitivity of 40.25 μA cm^-2 （mmol/L）^-1, low detection limit of 0.02 mmol/L, and a linear range from 0.02 to 3 mmol/L.

关 键 词：葡萄糖生物传感器 金纳米线阵列 修饰电极 石墨 检测 高分辨透射电子显微镜 场发射扫描电子显微镜 电流型 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置]